Pemetrexed Disodium Heptahydrate
- $23 - $1732.5
- Product name: Pemetrexed Disodium Heptahydrate
- CAS: 357166-29-1
- MF: C20H24N5NaO7
- MW: 469.43
- EINECS:639-569-0
- MDL Number:MFCD09029394
- Synonyms:N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate;Pemetrexed disodium hepthydrate;PeMetrexed disodiuM 7-hydrate;L-GlutaMic acid, N-[4-[2-(2-aMino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]-, disodiuM salt, heptahydrate;Pemetrexed for system suitability;Pemetrexed (sodium salt hydrate);N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hepthydrate;7-dihydro-4-oxo-3H-pyrrolo[2
19 prices
Selected condition:
Brand
- Ambeed
- American Custom Chemicals Corporation
- Cayman Chemical
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 5MG
- 10MG
- 50mg
- 100MG
- y0001538
- 250mg
- 500mg
- y0001539
- 1g
- 5g
- 25g
- ManufacturerAmbeed
- Product numberA209789
- Product descriptionSodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+%
- Packaging1g
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA209789
- Product descriptionSodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+%
- Packaging5g
- Price$93
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA209789
- Product descriptionSodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+%
- Packaging25g
- Price$372
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024628
- Product descriptionPEMETREXED DISODIUM HEPTAHYDRATE 95.00%
- Packaging5MG
- Price$171.6
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024628
- Product descriptionPEMETREXED DISODIUM HEPTAHYDRATE 95.00%
- Packaging10MG
- Price$721.88
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024628
- Product descriptionPEMETREXED DISODIUM HEPTAHYDRATE 95.00%
- Packaging100MG
- Price$1732.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14269
- Product descriptionPemetrexed (sodium salt hydrate) ≥98%
- Packaging5mg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14269
- Product descriptionPemetrexed (sodium salt hydrate) ≥98%
- Packaging10mg
- Price$112
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14269
- Product descriptionPemetrexed (sodium salt hydrate) ≥98%
- Packaging50mg
- Price$468
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14269
- Product descriptionPemetrexed (sodium salt hydrate) ≥98%
- Packaging100mg
- Price$816
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number66649
- Product descriptionPemetrexed disodium heptahydrate
- Packaging250mg
- Price$1475
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number66649
- Product descriptionPemetrexed disodium heptahydrate
- Packaging10mg
- Price$610
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberPHR1596
- Product descriptionPemetrexed for system suitability
- Packaging500mg
- Price$105
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1490
- Product descriptionPemetrexed for system suitability ≥98% (HPLC)
- Packaging10mg
- Price$108
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberY0001539
- Product descriptionPemetrexed disodium heptahydrate European Pharmacopoeia (EP) Reference Standard
- Packagingy0001539
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberY0001538
- Product descriptionPemetrexed for system suitability European Pharmacopoeia (EP) Reference Standard
- Packagingy0001538
- Price$153
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Ambeed | A209789 | Sodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+% | 1g | $23 | 2021-12-16 | Buy |
Ambeed | A209789 | Sodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+% | 5g | $93 | 2021-12-16 | Buy |
Ambeed | A209789 | Sodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+% | 25g | $372 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024628 | PEMETREXED DISODIUM HEPTAHYDRATE 95.00% | 5MG | $171.6 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024628 | PEMETREXED DISODIUM HEPTAHYDRATE 95.00% | 10MG | $721.88 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024628 | PEMETREXED DISODIUM HEPTAHYDRATE 95.00% | 100MG | $1732.5 | 2021-12-16 | Buy |
Cayman Chemical | 14269 | Pemetrexed (sodium salt hydrate) ≥98% | 5mg | $61 | 2024-03-01 | Buy |
Cayman Chemical | 14269 | Pemetrexed (sodium salt hydrate) ≥98% | 10mg | $112 | 2024-03-01 | Buy |
Cayman Chemical | 14269 | Pemetrexed (sodium salt hydrate) ≥98% | 50mg | $468 | 2024-03-01 | Buy |
Cayman Chemical | 14269 | Pemetrexed (sodium salt hydrate) ≥98% | 100mg | $816 | 2024-03-01 | Buy |
Medical Isotopes, Inc. | 66649 | Pemetrexed disodium heptahydrate | 250mg | $1475 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 66649 | Pemetrexed disodium heptahydrate | 10mg | $610 | 2021-12-16 | Buy |
Sigma-Aldrich | PHR1596 | Pemetrexed for system suitability | 500mg | $105 | 2024-03-01 | Buy |
Sigma-Aldrich | SML1490 | Pemetrexed for system suitability ≥98% (HPLC) | 10mg | $108 | 2024-03-01 | Buy |
Sigma-Aldrich | Y0001539 | Pemetrexed disodium heptahydrate European Pharmacopoeia (EP) Reference Standard | y0001539 | $153 | 2024-03-01 | Buy |
Sigma-Aldrich | Y0001538 | Pemetrexed for system suitability European Pharmacopoeia (EP) Reference Standard | y0001538 | $153 | 2024-03-01 | Buy |
Properties
storage temp. :2-8°C
solubility :H2O: soluble30mg/mL, clear
form :powder
color :white to beige
Stability :Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 31month.
InChIKey :AEZRDYKQLPDYEH-YTCXBBKHNA-N
SMILES :C(C1=CNC2NC(N)=NC(=O)C1=2)CC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[NaH].O |&1:20,r|
solubility :H2O: soluble30mg/mL, clear
form :powder
color :white to beige
Stability :Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 31month.
InChIKey :AEZRDYKQLPDYEH-YTCXBBKHNA-N
SMILES :C(C1=CNC2NC(N)=NC(=O)C1=2)CC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[NaH].O |&1:20,r|
Safety Information
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Description
Pemetrexed is pyrrotopyrimidine-based, multi-targeted antifolate with broad in vivo antitumor activity. Originally identified as a highly efficient substrate for folylpolyglutamate synthase, pemetrexed potently inhibits multiple folate-dependent enzymes involved in both purine and pyrimidine synthesis including thymidylate synthase (Ki = 109 nM), dihydrofolate reductase (Ki = 7 nM), glycinamide ribonucleotide formyltransferase (Ki = 9.3 μM), and aminoimidazole carboxamide ribonucleotide formyltransferase (Ki = 3.6 μM). Its antiproliferative activity has been demonstrated in a wide variety of solid tumors, including non-small cell lung, breast, mesothelioma, colorectal, pancreatic, gastric, bladder, cervix, and head and neck.More related product prices
4-(4-Hydroxybutyl)benzoic acid Methyl ester Methyl 4-bromobenzoate N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate Pemetrexed disodium 3-Buten-1-ol Methyl 4-(4-hydroxybut-1-ynyl)benzoate 3-Butyn-1-ol 2,4-Diamino-6-hydroxypyrimidine 137281-39-1 155405-80-4 PeMetrexed EP IMpurity A 4-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester 5-BroMopyriMidine-2,4,6(1H,3H,5H)-trioneRelated product price
Suppliers and manufacturers
career henan chemical co
Shanghai Daken Advanced Materials Co.,Ltd
Jinan Shengqi pharmaceutical Co,Ltd
Hubei Jusheng Technology Co.,Ltd.
Shandong ruiyue Biological Technology Co.,Ltd.
Shanghai Longyu Biotechnology Co., Ltd.
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
$2000.00 /1KG
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate CAS:357166-29-1
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid disodium salt hydrate CAS:357166-29-1