2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE
- $28 - $609
- Product name: 2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE
- CAS: 349085-38-7
- MF: C18H21N5O3
- MW: 355.39
- EINECS:
- MDL Number:MFCD02007349
- Synonyms:2-(1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL)-N-(4-ISOPROPYLPHENYL)ACETAMIDE;HC 030031;2-(1,3-dimethyl-2,6-dioxo-2,3-dihydro-1H-purin-7(6H)-yl)-N-(4-isopropylphenyl)acetamide;1,2,3,6-Tetrahydro-1,3-diMethyl-N-[4-(1-Methylethyl)phenyl]-2,6-dioxo-7H-purine-7-acetaMide;7H-Purine-7-acetamide, 1,2,3,6-tetrahydro-1,3-dimethyl-N-[4-(1-methylethyl)phenyl]-2,6-dioxo-;HC-030031;HC 030031;HC030031;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide;HC 030031 1G
21 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10mg
- 50
- 5mg
- 50mg
- 10
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number2459AH
- Product description2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide
- Packaging10mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2100
- Product descriptionHC-030031
- Packaging10mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545811
- Product descriptionHC-030031 >98%
- Packaging10mg
- Price$154.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545811
- Product descriptionHC-030031 >98%
- Packaging50mg
- Price$299.2
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH23741
- Product descriptionHC 030031
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH23741
- Product descriptionHC 030031
- Packaging50mg
- Price$228
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11923
- Product descriptionHC-030031 ≥98%
- Packaging5mg
- Price$28
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11923
- Product descriptionHC-030031 ≥98%
- Packaging10mg
- Price$48
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11923
- Product descriptionHC-030031 ≥98%
- Packaging50mg
- Price$140
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1040
- Product descriptionHC-030031 95.91%
- Packaging10mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1040
- Product descriptionHC-030031 95.91%
- Packaging50mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1040
- Product descriptionHC-030031 95.91%
- Packaging100mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002152
- Product descriptionHC-030031 98+%
- Packaging10mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002152
- Product descriptionHC-030031 98+%
- Packaging50mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002152
- Product descriptionHC-030031 98+%
- Packaging100mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC5200
- Product descriptionHC-030031 >98%
- Packaging100mg
- Price$250
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2459AH | 2-(1,3-Dimethyl-2,6-dioxopurin-7-yl)-N-(4-propan-2-ylphenyl)acetamide | 10mg | $137 | 2021-12-16 | Buy |
ApexBio Technology | B2100 | HC-030031 | 10mg | $45 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545811 | HC-030031 >98% | 10mg | $154.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb545811 | HC-030031 >98% | 50mg | $299.2 | 2021-12-16 | Buy |
Biosynth Carbosynth | FH23741 | HC 030031 | 10mg | $65 | 2021-12-16 | Buy |
Biosynth Carbosynth | FH23741 | HC 030031 | 50mg | $228 | 2021-12-16 | Buy |
Cayman Chemical | 11923 | HC-030031 ≥98% | 5mg | $28 | 2024-03-01 | Buy |
Cayman Chemical | 11923 | HC-030031 ≥98% | 10mg | $48 | 2024-03-01 | Buy |
Cayman Chemical | 11923 | HC-030031 ≥98% | 50mg | $140 | 2024-03-01 | Buy |
ChemScene | CS-1040 | HC-030031 95.91% | 10mg | $50 | 2021-12-16 | Buy |
ChemScene | CS-1040 | HC-030031 95.91% | 50mg | $120 | 2021-12-16 | Buy |
ChemScene | CS-1040 | HC-030031 95.91% | 100mg | $180 | 2021-12-16 | Buy |
Crysdot | CD31002152 | HC-030031 98+% | 10mg | $55 | 2021-12-16 | Buy |
Crysdot | CD31002152 | HC-030031 98+% | 50mg | $158 | 2021-12-16 | Buy |
Crysdot | CD31002152 | HC-030031 98+% | 100mg | $198 | 2021-12-16 | Buy |
DC Chemicals | DC5200 | HC-030031 >98% | 100mg | $250 | 2021-12-16 | Buy |
Properties
Melting point :221-223°C
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble10mg/mL, clear
pka :13.71±0.70(Predicted)
form :White solid
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :HEQDZPHDVAOBLN-UHFFFAOYSA-N
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble10mg/mL, clear
pka :13.71±0.70(Predicted)
form :White solid
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :HEQDZPHDVAOBLN-UHFFFAOYSA-N
Safety Information
Symbol(GHS): | |||||||||||||||||
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Signal word: | Danger | ||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Transient receptor potential cation channel A1 (TRPA1) is an ankyrin-like ion channel which acts as a sensor for chemical irritants, pain, and cold. It is activated by allyl isothiocyanate (AITC), formalin, hydrogen peroxide, tear gas, and other compounds. HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 μM, respectively). It does not block currents mediated by TRPV1, TRPV3, TRPV4 hERG, or NaV1.2 channels. HC-030031 can be used in cells or delivered to animals orally, by inhalation, or by injection. Oral administration (100 mg/kg) of HC-030031 significantly reversed mechanical hypersensitivity in rat models of chronic inflammatory or neuropathic pain, while local injection (100 μg) into inflamed mouse hind paws attenuated mechanical, but not heat, hypersensitivity.More related product prices
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