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ChemicalBook >> CAS DataBase List >> 3-Butylidenephthalide

3-Butylidenephthalide

3-Butylidenephthalide price.
  • $31.65 - $725
  • Product name: 3-Butylidenephthalide
  • CAS: 551-08-6
  • MF: C12H12O2
  • MW: 188.22
  • EINECS:208-991-3
  • MDL Number:MFCD00047319
  • Synonyms:N-BUTYLIDENEPHTHALIDE;FEMA 3333;1(3H)-Isobenzofuranone,3-butylidene- ;3-butylidene-1(3h)-isobenzofuranon ;3-butylidene-1(3H)-Isobenzofuranone ;3-BUTYLIDENEPHTHALIDE 96+%;n-Butylidenephthalide,95%;3-Butylidene-1,3-dihydroisobenzofuran-1-one
24 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 5MG
  • 20mg
  • 25mg
  • 200mg
  • 1g
  • 10g
  • 25g
  • 50g
  • 100g
  • 250g
  • 500g
  • ManufacturerAK Scientific
  • Product numberY0142
  • Product descriptionn-Butylidenephthalide(mixtureofisomers)
  • Packaging500g
  • Price$725
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA10353
  • Product descriptionn-Butylidenephthalide, (E)+(Z), 95%
  • Packaging10g
  • Price$31.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA10353
  • Product descriptionn-Butylidenephthalide, (E)+(Z), 95%
  • Packaging50g
  • Price$90.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA10353
  • Product descriptionn-Butylidenephthalide, (E)+(Z), 95%
  • Packaging250g
  • Price$342
  • Updated2023-06-20
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberFFG0002791
  • Product description3-BUTYLIDENEPHTHALIDE 95.00%
  • Packaging5MG
  • Price$451.72
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2583
  • Product description3-Butylidenephthalide
  • Packaging200mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99588
  • Product description3-Butylidenephthalide
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022827
  • Product description3-Butylideneisobenzofuran-1(3H)-one 97%
  • Packaging25g
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022827
  • Product description3-Butylideneisobenzofuran-1(3H)-one 97%
  • Packaging100g
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022827
  • Product description3-Butylideneisobenzofuran-1(3H)-one 97%
  • Packaging500g
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3657
  • Product description3-Butylidenephthalide
  • Packaging5mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3657
  • Product description3-Butylidenephthalide
  • Packaging25mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb593697
  • Product description3-Butylidenephthalide
  • Packaging20mg
  • Price$513.4
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb104762
  • Product descriptionn-Butylidenephthalide >98%,Standard References Grade
  • Packaging20mg
  • Price$569.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19574
  • Product description3-Butylidene phthalide - mixture of?cis?and?trans?isomers
  • Packaging25g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19574
  • Product description3-Butylidene phthalide - mixture of?cis?and?trans?isomers
  • Packaging50g
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0142 n-Butylidenephthalide(mixtureofisomers) 500g $725 2021-12-16 Buy
Alfa Aesar A10353 n-Butylidenephthalide, (E)+(Z), 95% 10g $31.65 2024-03-01 Buy
Alfa Aesar A10353 n-Butylidenephthalide, (E)+(Z), 95% 50g $90.65 2024-03-01 Buy
Alfa Aesar A10353 n-Butylidenephthalide, (E)+(Z), 95% 250g $342 2023-06-20 Buy
American Custom Chemicals Corporation FFG0002791 3-BUTYLIDENEPHTHALIDE 95.00% 5MG $451.72 2021-12-16 Buy
ApexBio Technology N2583 3-Butylidenephthalide 200mg $90 2021-12-16 Buy
Arctom CFN99588 3-Butylidenephthalide 20mg $40 2021-12-16 Buy
Arctom AS022827 3-Butylideneisobenzofuran-1(3H)-one 97% 25g $42 2021-12-16 Buy
Arctom AS022827 3-Butylideneisobenzofuran-1(3H)-one 97% 100g $106 2021-12-16 Buy
Arctom AS022827 3-Butylideneisobenzofuran-1(3H)-one 97% 500g $390 2021-12-16 Buy
AvaChem 3657 3-Butylidenephthalide 5mg $190 2021-12-16 Buy
AvaChem 3657 3-Butylidenephthalide 25mg $390 2021-12-16 Buy
Biorbyt Ltd orb593697 3-Butylidenephthalide 20mg $513.4 2021-12-16 Buy
Biorbyt Ltd orb104762 n-Butylidenephthalide >98%,Standard References Grade 20mg $569.5 2021-12-16 Buy
Biosynth Carbosynth FB19574 3-Butylidene phthalide - mixture of?cis?and?trans?isomers 25g $65 2021-12-16 Buy
Biosynth Carbosynth FB19574 3-Butylidene phthalide - mixture of?cis?and?trans?isomers 50g $100 2021-12-16 Buy

Properties

Melting point :82.5°C
Boiling point :139-142 °C/5 mmHg (lit.)
Density :1.103 g/mL at 25 °C (lit.)
FEMA :3333 | 3-BUTYLIDENEPHTHALIDE
refractive index :n20/D 1.577(lit.)
Flash point :>230 °F
storage temp. :Refrigerator
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Oil
color :Colourless to Yellow
Odor :at 10.00 % in dipropylene glycol. herbal lovage celery
Odor Type :herbal
JECFA Number :1170
BRN :5145
InChIKey :WMBOCUXXNSOQHM-FLIBITNWSA-N
LogP :3.72
CAS DataBase Reference :551-08-6(CAS DataBase Reference)
EPA Substance Registry System :1(3H)-Isobenzofuranone, 3-butylidene- (551-08-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

Description

N-Butylidenephthalide is a phthalide derivative useful for control of sensation disorder and olfaction disorder. It is a bioactive phthalide compound of Chuanxiong rhizoma, a Chinese herbal medicine used for treating headache obtained from the root of Ligusticum chuanxiong Hort. It has found that it can regulate tumor stem cell genes EZH2/AXL and reduced its migration and invasion in glioblastoma. Moreover, it can induce apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2a and telomerase activity. Therefore, it is a potential cancer chemotherapy drug. Moreover, It can also exhibit protection against neurotoxicity through regulation of tryptophan 2, 3 dioxygenase in spinocerebellar ataxia type 3. Finally, it has certain antiplatelet effect.

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