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ChemicalBook >> CAS DataBase List >> Diethyl cyanomethylphosphonate

Diethyl cyanomethylphosphonate

Diethyl cyanomethylphosphonate price.
  • $7 - $1056.65
  • Product name: Diethyl cyanomethylphosphonate
  • CAS: 2537-48-6
  • MF: C6H12NO3P
  • MW: 177.14
  • EINECS:219-806-0
  • MDL Number:MFCD00001893
  • Synonyms:Diethyl cyanoMethylphosphonate, 96% 10GR;Diethyl cyanoMethylphosphonate, 96% 50GR;Phosphonicacid, P-(cyanoMethyl)-, diethyl ester;With diethyl Methyl phosphoric acid;Diethyl cyanomethylphosphote;(Cyanomethyl)diethoxyphosphine oxide;2-(Diethylphosphonyl)acetonitrile;Diethyl cyanomethanephosphonate
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  • ManufacturerAcrotein
  • Product numberAC-7425
  • Product descriptionDiethyl cyanomethylphosphonate 97%
  • Packaging500g
  • Price$176.92
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ20469
  • Product descriptionDiethyl cyanomethylphosphonate
  • Packaging25g
  • Price$82.7
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ90229
  • Product descriptionDiethyl cyanomethylphosphonate
  • Packaging500g
  • Price$180
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberA10218
  • Product descriptionDiethyl cyanomethylphosphonate, 98+%
  • Packaging25g
  • Price$91.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberA10218
  • Product descriptionDiethyl cyanomethylphosphonate, 98+%
  • Packaging100g
  • Price$326
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberA10218
  • Product descriptionDiethyl cyanomethylphosphonate, 98+%
  • Packaging500g
  • Price$1056.65
  • Updated2024-03-01
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  • ManufacturerAmbeed
  • Product numberA228076
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging10g
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA228076
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging25g
  • Price$10
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA228076
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging100g
  • Price$18
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA228076
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging1kg
  • Price$118
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0255135
  • Product description2-CHLORO-3-(3-METHOXYPROPYLAMINO)NAPHTHALENE-1,4-DIONE 95.00%
  • Packaging5MG
  • Price$504.94
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR6821
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging25g
  • Price$18
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR6821
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging100g
  • Price$58
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR6821
  • Product descriptionDiethyl cyanomethylphosphonate 98%
  • Packaging250g
  • Price$124
  • Updated2021-12-16
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  • ManufacturerAtlantic Research Chemicals
  • Product numberXS10195
  • Product descriptionDiethyl cyanomethylphosphonate 95%
  • Packaging50gm:
  • Price$60.09
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFD11127
  • Product descriptionDiethyl cyanomethylphosphonate
  • Packaging100g
  • Price$45
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
Acrotein AC-7425 Diethyl cyanomethylphosphonate 97% 500g $176.92 2021-12-16 Buy
AK Scientific J20469 Diethyl cyanomethylphosphonate 25g $82.7 2021-12-16 Buy
AK Scientific J90229 Diethyl cyanomethylphosphonate 500g $180 2021-12-16 Buy
Alfa Aesar A10218 Diethyl cyanomethylphosphonate, 98+% 25g $91.65 2024-03-01 Buy
Alfa Aesar A10218 Diethyl cyanomethylphosphonate, 98+% 100g $326 2024-03-01 Buy
Alfa Aesar A10218 Diethyl cyanomethylphosphonate, 98+% 500g $1056.65 2024-03-01 Buy
Ambeed A228076 Diethyl cyanomethylphosphonate 98% 10g $7 2021-12-16 Buy
Ambeed A228076 Diethyl cyanomethylphosphonate 98% 25g $10 2021-12-16 Buy
Ambeed A228076 Diethyl cyanomethylphosphonate 98% 100g $18 2021-12-16 Buy
Ambeed A228076 Diethyl cyanomethylphosphonate 98% 1kg $118 2021-12-16 Buy
American Custom Chemicals Corporation HCH0255135 2-CHLORO-3-(3-METHOXYPROPYLAMINO)NAPHTHALENE-1,4-DIONE 95.00% 5MG $504.94 2021-12-16 Buy
Apolloscientific OR6821 Diethyl cyanomethylphosphonate 98% 25g $18 2021-12-16 Buy
Apolloscientific OR6821 Diethyl cyanomethylphosphonate 98% 100g $58 2021-12-16 Buy
Apolloscientific OR6821 Diethyl cyanomethylphosphonate 98% 250g $124 2021-12-16 Buy
Atlantic Research Chemicals XS10195 Diethyl cyanomethylphosphonate 95% 50gm: $60.09 2021-12-16 Buy
Biosynth Carbosynth FD11127 Diethyl cyanomethylphosphonate 100g $45 2021-12-16 Buy

Properties

Boiling point :101-102 °C0.4 mm Hg(lit.)
Density :1.095 g/mL at 25 °C(lit.)
refractive index :n20/D 1.434(lit.)
Flash point :>230 °F
storage temp. :Inert atmosphere,2-8°C
solubility :Chloroform (Soluble), Methanol (Slightly)
form :Liquid
color :Clear colorless to light yellow
Specific Gravity :1.1261.095
Water Solubility :Miscible with water, chloroform, terahydrofuran, ethyl acetate and methylene chloride.
BRN :1772981
InChI :InChI=1S/C6H12NO3P/c1-3-9-11(8,6-5-7)10-4-2/h3-4,6H2,1-2H3
InChIKey :KWMBADTWRIGGGG-UHFFFAOYSA-N
SMILES :P(CC#N)(=O)(OCC)OCC
CAS DataBase Reference :2537-48-6(CAS DataBase Reference)
NIST Chemistry Reference :Diethyl cyanomethylphosphonate(2537-48-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger GHS hazard pictograms P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Diethyl cyanomethyl phosphonate is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI.

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