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ChemicalBook >> CAS DataBase List >> 2-Deoxy-D-glucose

2-Deoxy-D-glucose

2-Deoxy-D-glucose price.
  • $6 - $3030
  • Product name: 2-Deoxy-D-glucose
  • CAS: 154-17-6
  • MF: C6H12O5
  • MW: 164.16
  • EINECS:205-823-0
  • MDL Number:MFCD00151328
  • Synonyms:2-deoxy-d-arabino-hexos ;2-deoxy-d-glucos ;2-deoxy-d-mannose ;2-deoxy-glucos ;D-2-GLUCODESOSE;2-DEOXY-D-GLUCOSE GRADE III F&D VERSION;2-DEOXY-D-GLUCOSE, 99%, MIXTURE OF ANOMERS;6-HYDROXYMETHYL-5-METHYL-TETRAHYDRO-PYRAN-2,4,5-TRIOL
75 prices
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  • Adipogen Life Sciences
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  • ApexBio Technology
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  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3681-G005
  • Product description2-Deoxy-D-glucose ≥98%
  • Packaging5G
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-07615
  • Product description2-Deoxy-D-glucose 99%
  • Packaging50g
  • Price$389
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3176AH
  • Product description2-Deoxy-D-glucose
  • Packaging1g
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99749
  • Product description2-Deoxy-D-glucose
  • Packaging25g
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99749
  • Product description2-Deoxy-D-glucose
  • Packaging100g
  • Price$470
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberL07338
  • Product description2-Deoxy-D-glucose, 98%
  • Packaging1g
  • Price$66.4
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberL07338
  • Product description2-Deoxy-D-glucose, 98%
  • Packaging5g
  • Price$243
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberL07338
  • Product description2-Deoxy-D-glucose, 98%
  • Packaging25g
  • Price$840
  • Updated2024-03-01
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  • ManufacturerAmbeed
  • Product numberA104420
  • Product description(3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal 98+%
  • Packaging250mg
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA104420
  • Product description(3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal 98+%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA104420
  • Product description(3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal 98+%
  • Packaging5g
  • Price$35
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA104420
  • Product description(3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal 98+%
  • Packaging25g
  • Price$117
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0007410
  • Product description(4R,5S,6R)-6-(HYDROXYMETHYL)OXANE-2,4,5-TRIOL 95.00%
  • Packaging5MG
  • Price$500.07
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0003752
  • Product description2-DEOXY-D-GLUCOSE 95.00%
  • Packaging250MG
  • Price$612.42
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1027
  • Product description2-Deoxy-D-glucose
  • Packaging1g
  • Price$40
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1027
  • Product description2-Deoxy-D-glucose
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3681-G005 2-Deoxy-D-glucose ≥98% 5G $180 2021-12-16 Buy
AHH MT-07615 2-Deoxy-D-glucose 99% 50g $389 2021-12-16 Buy
AK Scientific 3176AH 2-Deoxy-D-glucose 1g $17 2021-12-16 Buy
AK Scientific J99749 2-Deoxy-D-glucose 25g $130 2021-12-16 Buy
AK Scientific J99749 2-Deoxy-D-glucose 100g $470 2021-12-16 Buy
Alfa Aesar L07338 2-Deoxy-D-glucose, 98% 1g $66.4 2024-03-01 Buy
Alfa Aesar L07338 2-Deoxy-D-glucose, 98% 5g $243 2024-03-01 Buy
Alfa Aesar L07338 2-Deoxy-D-glucose, 98% 25g $840 2024-03-01 Buy
Ambeed A104420 (3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal 98+% 250mg $6 2021-12-16 Buy
Ambeed A104420 (3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal 98+% 1g $11 2021-12-16 Buy
Ambeed A104420 (3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal 98+% 5g $35 2021-12-16 Buy
Ambeed A104420 (3R,4S,5R)-3,4,5,6-Tetrahydroxyhexanal 98+% 25g $117 2021-12-16 Buy
American Custom Chemicals Corporation CCH0007410 (4R,5S,6R)-6-(HYDROXYMETHYL)OXANE-2,4,5-TRIOL 95.00% 5MG $500.07 2021-12-16 Buy
American Custom Chemicals Corporation INB0003752 2-DEOXY-D-GLUCOSE 95.00% 250MG $612.42 2021-12-16 Buy
ApexBio Technology B1027 2-Deoxy-D-glucose 1g $40 2021-12-16 Buy
ApexBio Technology B1027 2-Deoxy-D-glucose 10mM(in 1mL DMSO) $55 2021-12-16 Buy

Properties

Melting point :146-147 °C(lit.)
alpha :45.5 º (c=2, H2O)
Boiling point :211.61°C (rough estimate)
Density :1.1738 (rough estimate)
refractive index :46.5 ° (C=1, H2O)
storage temp. :2-8°C
solubility :H2O: 50 mg/mL, clear, colorless to faintly yellow
pka :pK1:12.52 (25°C)
form :crystalline
color :white
optical activity :+38.5 → +45.9
Water Solubility :Soluble in water.
Merck :14,2904
BRN :1723331
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. Solutions in water are not stable and must be used within 1 working day.
InChIKey :PMMURAAUARKVCB-CEZCPVKQSA-N
LogP :-1.460 (est)
CAS DataBase Reference :154-17-6(CAS DataBase Reference)
EPA Substance Registry System :D-arabino-Hexose, 2-deoxy- (154-17-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

2-deoxy-D-Glucose is a non-metabolizable glucose analog that inhibits phosphorylation of glucose by hexokinase, the first step of glycolysis. This results in the depletion in cellular ATP, the inhibition of protein glycosylation, and the disruption of ER quality control by inducing the unfolded protein response. 2-deoxy-D-Glucose has been shown to cause cell cycle inhibition and cell death in in vitro models of hypoxia, induce autophagy, increase reactive oxygen species production, activate AMPK, and block tumor cell growth in animal models.

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