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ChemicalBook >> CAS DataBase List >> 1-HEXADECANOYL-2-(P-NITROPHENOXYSUCCINOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE

1-HEXADECANOYL-2-(P-NITROPHENOXYSUCCINOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE

1-HEXADECANOYL-2-(P-NITROPHENOXYSUCCINOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE price.
  • $32 - $1450
  • Product name: 1-HEXADECANOYL-2-(P-NITROPHENOXYSUCCINOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
  • CAS: 170569-87-6
  • MF: C16H12F3N3O2S
  • MW: 367.35
  • EINECS:
  • MDL Number:MFCD03453540
  • Synonyms:4-[5-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOL-1-YL]BENZENESULFONAMIDE;PTPBS;Celecoxib Impurity 3;COX-2 INHIBITOR, PTPBS;CAY10452;CAY10454;[3',6'-BIS(ACETYLOXY)-3-OXOSPIRO[ISOBENZOFURAN-1(3H),9'-[9H]XANTHEN]-5-YL]-2-[[(5Z,8Z,11Z,14Z)-1-OXO-5,8,11,14-EICOSATETRAENYL]AMINO]ETHYL ESTER CARBAMIC ACID;4-[5-PHENYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
15 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 002
  • 50mg
  • 100mg
  • 001
  • 250mg
  • ManufacturerAK Scientific
  • Product number8232CP
  • Product description4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8232CP
  • Product description4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • Packaging10mg
  • Price$286
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8232CP
  • Product description4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • Packaging25mg
  • Price$496
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1143654
  • Product description4-(5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 98+%
  • Packaging100mg
  • Price$501
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1143654
  • Product description4-(5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 98+%
  • Packaging250mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10075
  • Product descriptionCAY10452 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10075
  • Product descriptionCAY10452 ≥98%
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10075
  • Product descriptionCAY10452 ≥98%
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10075
  • Product descriptionCAY10452 ≥98%
  • Packaging25mg
  • Price$357
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0065275
  • Product descriptionDesmethylCelecoxib 99.09%
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0065275
  • Product descriptionDesmethylCelecoxib 99.09%
  • Packaging25mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0065275
  • Product descriptionDesmethylCelecoxib 99.09%
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-0065275
  • Product descriptionDesmethylCelecoxib 99.09%
  • Packaging100mg
  • Price$250
  • Updated2021-12-16
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  • ManufacturerDC Chemicals
  • Product number012436
  • Product descriptionDesmethylCelecoxib
  • Packaging001
  • Price$850
  • Updated2021-12-16
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  • ManufacturerDC Chemicals
  • Product number012436
  • Product descriptionDesmethylCelecoxib
  • Packaging002
  • Price$1450
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8232CP 4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide 1mg $133 2021-12-16 Buy
AK Scientific 8232CP 4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide 10mg $286 2021-12-16 Buy
AK Scientific 8232CP 4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide 25mg $496 2021-12-16 Buy
Ambeed A1143654 4-(5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 98+% 100mg $501 2021-12-16 Buy
Ambeed A1143654 4-(5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 98+% 250mg $750 2021-12-16 Buy
Cayman Chemical 10075 CAY10452 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 10075 CAY10452 ≥98% 5mg $100 2024-03-01 Buy
Cayman Chemical 10075 CAY10452 ≥98% 10mg $169 2024-03-01 Buy
Cayman Chemical 10075 CAY10452 ≥98% 25mg $357 2024-03-01 Buy
ChemScene CS-0065275 DesmethylCelecoxib 99.09% 10mg $50 2021-12-16 Buy
ChemScene CS-0065275 DesmethylCelecoxib 99.09% 25mg $90 2021-12-16 Buy
ChemScene CS-0065275 DesmethylCelecoxib 99.09% 50mg $150 2021-12-16 Buy
ChemScene CS-0065275 DesmethylCelecoxib 99.09% 100mg $250 2021-12-16 Buy
DC Chemicals 012436 DesmethylCelecoxib 001 $850 2021-12-16 Buy
DC Chemicals 012436 DesmethylCelecoxib 002 $1450 2021-12-16 Buy

Properties

Melting point :158-160 °C(Solv: ethanol (64-17-5))
Boiling point :522.5±60.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:8): 0.1 mg/ml
form :A crystalline solid
pka :9.68±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Inhibitors of cyclooxygenase (COX) are generally grouped according to selectivity for COX-1 versus COX-2. However, many COX inhibitors also show an antitumor, pro-apoptotic activity that is distinct from COX inhibition - celecoxib is an example. CAY10452 is a celecoxib analog that retains potent, selective COX-2 inhibitory activity (IC50 = 32 nM), but does not induce apoptosis in prostate cancer cell lines even at 100 μM. CAY10452 is thus a clean, selective tool for the inhibition of COX-2.