1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE
![1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE price.](/CAS/GIF/162054-19-5.gif)
|
- $17 - $4718
- Product name: 1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE
- CAS: 162054-19-5
- MF: C17H12F4N2O2S
- MW: 384.35
- EINECS:
- MDL Number:MFCD00930300
- Synonyms:SC-58125;1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE;5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)pyrazole;5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole;5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3-trifluoromethyl-1H-pyrazole;1H-Pyrazole, 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-;Cyclooxygenase,cancer,SC58125,COX,Inhibitor,SC-58125,inflammatory,antitumor,COX-2,edema,inhibit
19 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- Chemenu
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 10
- 0.025g
- 25mg
- 50mg
- 100mg
- ManufacturerAHH
- Product numberMT-18860
- Product description1-[(4-Methylsulfonyl)phenyl]-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole 98%
- Packaging0.025g
- Price$415
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1132AH
- Product description1-[(4-Methylsulfonyl)phenyl]-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole
- Packaging1mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1132AH
- Product description1-[(4-Methylsulfonyl)phenyl]-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole
- Packaging10mg
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA432665
- Product description5-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole 98+%
- Packaging10mg
- Price$186
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA432665
- Product description5-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole 98+%
- Packaging25mg
- Price$315
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA432665
- Product description5-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole 98+%
- Packaging50mg
- Price$473
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5347
- Product descriptionSC58125
- Packaging10mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number70655
- Product descriptionSC-58125 ≥98%
- Packaging1mg
- Price$17
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70655
- Product descriptionSC-58125 ≥98%
- Packaging5mg
- Price$67
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70655
- Product descriptionSC-58125 ≥98%
- Packaging10mg
- Price$118
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70655
- Product descriptionSC-58125 ≥98%
- Packaging25mg
- Price$257
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM331359
- Product description5-(4-fluorophenyl)-1-(4-methylsulfonylphenyl)-3-(trifluoromethyl)pyrazole 95%+
- Packaging100mg
- Price$4718
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM331359
- Product description5-(4-fluorophenyl)-1-(4-methylsulfonylphenyl)-3-(trifluoromethyl)pyrazole 95%+
- Packaging50mg
- Price$2408
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number52994
- Product descriptionSC-58125
- Packaging10mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberPZ0139
- Product descriptionSC-58125 ≥98% (HPLC)
- Packaging25mg
- Price$404
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberPZ0139
- Product descriptionSC-58125 ≥98% (HPLC)
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-18860 | 1-[(4-Methylsulfonyl)phenyl]-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole 98% | 0.025g | $415 | 2021-12-16 | Buy |
| AK Scientific | 1132AH | 1-[(4-Methylsulfonyl)phenyl]-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole | 1mg | $116 | 2021-12-16 | Buy |
| AK Scientific | 1132AH | 1-[(4-Methylsulfonyl)phenyl]-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole | 10mg | $229 | 2021-12-16 | Buy |
| Ambeed | A432665 | 5-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole 98+% | 10mg | $186 | 2021-12-16 | Buy |
| Ambeed | A432665 | 5-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole 98+% | 25mg | $315 | 2021-12-16 | Buy |
| Ambeed | A432665 | 5-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole 98+% | 50mg | $473 | 2021-12-16 | Buy |
| ApexBio Technology | B5347 | SC58125 | 10mg | $245 | 2021-12-16 | Buy |
| Cayman Chemical | 70655 | SC-58125 ≥98% | 1mg | $17 | 2024-03-01 | Buy |
| Cayman Chemical | 70655 | SC-58125 ≥98% | 5mg | $67 | 2024-03-01 | Buy |
| Cayman Chemical | 70655 | SC-58125 ≥98% | 10mg | $118 | 2024-03-01 | Buy |
| Cayman Chemical | 70655 | SC-58125 ≥98% | 25mg | $257 | 2024-03-01 | Buy |
| Chemenu | CM331359 | 5-(4-fluorophenyl)-1-(4-methylsulfonylphenyl)-3-(trifluoromethyl)pyrazole 95%+ | 100mg | $4718 | 2021-12-16 | Buy |
| Chemenu | CM331359 | 5-(4-fluorophenyl)-1-(4-methylsulfonylphenyl)-3-(trifluoromethyl)pyrazole 95%+ | 50mg | $2408 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 52994 | SC-58125 | 10mg | $640 | 2021-12-16 | Buy |
| Sigma-Aldrich | PZ0139 | SC-58125 ≥98% (HPLC) | 25mg | $404 | 2024-03-01 | Buy |
| Sigma-Aldrich | PZ0139 | SC-58125 ≥98% (HPLC) | 5mg | $109 | 2024-03-01 | Buy |
Properties
storage temp. :Store at +4°C
solubility :DMSO: ≥20mg/mL
form :powder
color :white to off-white
solubility :DMSO: ≥20mg/mL
form :powder
color :white to off-white
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
SC-58125 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK 966 (rofecoxib), DUP-697, and celecoxib. SC-58125 is a potent and time-dependent inhibitor of COX-2. When tested on the isolated recombinant enzymes, SC-58125 is at least 150 times more potent in the inhibition of COX-2 as COX-1. In cultured HUVEC cells, SC-58125 inhibits COX-2 with an IC50 of 70 nM. It also inhibits the growth of the COX-2 expressing cell line HCA-7 in nude mice at 5-10 mg/kg when given intraperitoneally.More related product prices
4'-Hydroxyacetophenone p-Tolualdehyde 2-Methylpropanedioic acid 16495-13-9 Octadecyl methacrylate 2-Methylindole 154258-82-9Related product price
- 4'-Hydroxyacetophenone
$5-437 - p-Tolualdehyde
$6-6310.57 - 2-Methylpropanedioic acid
$10-2148.3
Suppliers and manufacturers
Alchem Pharmtech,Inc.
Amadis Chemical Company Limited
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
Chemsky（shanghai）International Co.,Ltd.
Guangzhou Isun Pharmaceutical Co., Ltd
Tianjin Kailiqi Biotechnology Co., Ltd.
MQ (shanghai) Pharmaceuticals Co., Ltd.
Shanghai Jizhi Biochemical Technology Co. Ltd.
