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ChemicalBook >> CAS DataBase List >> Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate price.
  • $11 - $909.56
  • Product name: Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
  • CAS: 160844-75-7
  • MF: C18H20N2O3S
  • MW: 344.43
  • EINECS:927-913-5
  • MDL Number:MFCD09833701
  • Synonyms:5-Thiazolecarboxylicacid, 2-[3-cyano-4-(2-Methylpropoxy)phenyl]-4-Methyl-, ethyl ester;2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate;ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl;Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate;Ethyl> 2-(3-cyano-4-isobutoxyphenyl)-4-Methyl-5-th;5-carboxylato-2-[3-cyano-4-(2-Methylpropoxy)phenyl]-1-ethyl-4-Methyl-1H-1$l^{4},3-thiazol-1-yl;ethyl ester of febuxostat;2-[3-cyano-4-(2-Methylpropoxy)phenyl]-4-Me
23 prices
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Brand
  • AK Scientific
  • Alichem
  • Ambeed
  • American Custom Chemicals Corporation
  • Ark Pharm
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TCI Chemical
  • TRC
Package
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • ManufacturerAK Scientific
  • Product numberW3489
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
  • Packaging1g
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number160844757
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
  • Packaging25g
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA311178
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging250mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA311178
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging1g
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA311178
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging5g
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA311178
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging10g
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA311178
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging25g
  • Price$227
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0068807
  • Product descriptionETHYL 2-(3-CYANO-4-ISOBUTOXYPHENYL)-4-METHYL-5-THIAZOLECARBOXYLATE 95.00%
  • Packaging5G
  • Price$909.56
  • Updated2021-12-16
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  • ManufacturerArk Pharm
  • Product numberP000219188
  • Product descriptionEthyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging250mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000219188
  • Product descriptionEthyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging5g
  • Price$83
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000219188
  • Product descriptionEthyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging10g
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000219188
  • Product descriptionEthyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97%
  • Packaging25g
  • Price$262
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM190022
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95%
  • Packaging10g
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM190022
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95%
  • Packaging25g
  • Price$206
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM190022
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95%
  • Packaging100g
  • Price$514
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11244602
  • Product descriptionEthyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95+%
  • Packaging25g
  • Price$218
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific W3489 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 1g $95 2021-12-16 Buy
Alichem 160844757 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 25g $220 2021-12-16 Buy
Ambeed A311178 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 250mg $11 2021-12-16 Buy
Ambeed A311178 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 1g $26 2021-12-16 Buy
Ambeed A311178 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 5g $76 2021-12-16 Buy
Ambeed A311178 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 10g $113 2021-12-16 Buy
Ambeed A311178 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 25g $227 2021-12-16 Buy
American Custom Chemicals Corporation CHM0068807 ETHYL 2-(3-CYANO-4-ISOBUTOXYPHENYL)-4-METHYL-5-THIAZOLECARBOXYLATE 95.00% 5G $909.56 2021-12-16 Buy
Ark Pharm P000219188 Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 250mg $12 2021-12-16 Buy
Ark Pharm P000219188 Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 5g $83 2021-12-16 Buy
Ark Pharm P000219188 Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 10g $131 2021-12-16 Buy
Ark Pharm P000219188 Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 97% 25g $262 2021-12-16 Buy
Chemenu CM190022 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95% 10g $112 2021-12-16 Buy
Chemenu CM190022 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95% 25g $206 2021-12-16 Buy
Chemenu CM190022 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95% 100g $514 2021-12-16 Buy
Crysdot CD11244602 Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 95+% 25g $218 2021-12-16 Buy

Properties

Melting point :176 °C
Boiling point :497.1±55.0 °C(Predicted)
Density :1.22
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)
form :Solid
pka :1.02±0.10(Predicted)
color :White to Off-White
InChI :InChI=1S/C18H20N2O3S/c1-5-22-18(21)16-12(4)20-17(24-16)13-6-7-15(14(8-13)9-19)23-10-11(2)3/h6-8,11H,5,10H2,1-4H3
InChIKey :OGAZOYHQFBSRMC-UHFFFAOYSA-N
SMILES :S1C(C(OCC)=O)=C(C)N=C1C1=CC=C(OCC(C)C)C(C#N)=C1
CAS DataBase Reference :160844-75-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.