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ChemicalBook >> CAS DataBase List >> (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide

(1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide

(1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide price.
  • $40 - $805
  • Product name: (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide
  • CAS: 1246303-14-9
  • MF: C25H29BrN4O2
  • MW: 497.43
  • EINECS:
  • MDL Number:MFCD22416858
  • Synonyms:(1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide;VU0359595;(1R,2R)-N-([S]-1-{4-[5-BROMO-2-OXO-2,3-DIHYDRO-1H-BENZO(D)IMIDAZOL-1-YL]PIPERIDIN-1-YL}PROPAN-2-YL)-2-PHENYLCYCLOPROPANECARBOXAMIDE;VU0359595;(1R,2R)-N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-2-phenylcyclopropane-1-carboxamide;Cyclopropanecarboxamide, N-[(1S)-2-[4-(5-bromo-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-phenyl-, (1R,2R)-;ML270
11 prices
Selected condition：
Brand
  • ApexBio Technology
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerApexBio Technology
  • Product numberC3919
  • Product descriptionVU0359595
  • Packaging5mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3919
  • Product descriptionVU0359595
  • Packaging10mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3919
  • Product descriptionVU0359595
  • Packaging25mg
  • Price$452
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10955
  • Product descriptionVU0359595 ≥95%
  • Packaging1mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10955
  • Product descriptionVU0359595 ≥95%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10955
  • Product descriptionVU0359595 ≥95%
  • Packaging10mg
  • Price$236
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10955
  • Product descriptionVU0359595 ≥95%
  • Packaging25mg
  • Price$541
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number73007
  • Product descriptionVU0359595
  • Packaging25mg
  • Price$805
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberV787565
  • Product descriptionVU0359595
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberV787565
  • Product descriptionVU0359595
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberV787565
  • Product descriptionVU0359595
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology C3919 VU0359595 5mg $111 2021-12-16 Buy
ApexBio Technology C3919 VU0359595 10mg $201 2021-12-16 Buy
ApexBio Technology C3919 VU0359595 25mg $452 2021-12-16 Buy
Cayman Chemical 10955 VU0359595 ≥95% 1mg $40 2024-03-01 Buy
Cayman Chemical 10955 VU0359595 ≥95% 5mg $139 2024-03-01 Buy
Cayman Chemical 10955 VU0359595 ≥95% 10mg $236 2024-03-01 Buy
Cayman Chemical 10955 VU0359595 ≥95% 25mg $541 2024-03-01 Buy
Medical Isotopes, Inc. 73007 VU0359595 25mg $805 2021-12-16 Buy
TRC V787565 VU0359595 1mg $50 2021-12-16 Buy
TRC V787565 VU0359595 5mg $85 2021-12-16 Buy
TRC V787565 VU0359595 10mg $150 2021-12-16 Buy

Properties

Density :1.395±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear
pka :11.11±0.30(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Phospholipase D (PLD) is an enzyme that cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1, and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are regulated differently and apparently subserve distinct roles. VU0359595 is an inhibitor of PLD1 (IC50 = 3.7 nM) that is >1,700-fold selective over PLD2 (IC50 = 6.4 μM). Preliminary evidence suggests that VU0359595 does not interact with the catalytic site of PLD, but instead may bind and inhibit PLD through an allosteric site.