Trimethylamine
Product identifier
- Product name: Trimethylamine
- CBnumber: CB6332996
- CAS: 75-50-3
- EINECS Number: 200-875-0
- Synonyms: Trimethylamine,Methylamine, N,N-dimethyl-
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Gases under pressure: Liquefied gas
Flammable gases, Category 1A, Flammable gas
Skin irritation, Category 2
Serious eye damage, Category 1
Acute toxicity - Category 4, Inhalation
Specific target organ toxicity – single exposure, Category 3
Label elements
Pictogram(s)
- Signal wordDanger
H220 Extremely flammable gas
H224 Extremely flammable liquid and vapour
H225 Highly Flammable liquid and vapour
H280 Contains gas under pressure; may explode if heated
H302 Harmful if swallowed
H314 Causes severe skin burns and eye damage
H315 Causes skin irritation
H318 Causes serious eye damage
H332 Harmful if inhaled
H333 May be harmful if inhaled
H335 May cause respiratory irritation
H351 Suspected of causing cancer
H402 Harmful to aquatic life
H412 Harmful to aquatic life with long lasting effects
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.
P410+P403 Protect from sunlight. Store in a well-ventilated place.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P381 In case of leakage, eliminate all ignition sources.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P410+P403 Protect from sunlight. Store in a well-ventilated place.
P403 Store in a well-ventilated place.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards
no data available
Substance
- Product name: Trimethylamine
- Synonyms: Trimethylamine,Methylamine, N,N-dimethyl-
- CAS: 75-50-3
- EC number: 200-875-0
- MF: C3H9N
- MW: 59.11
Description of first aid measures
If inhaledFresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
no data available
Extinguishing media
Use dry chemical, carbon dioxide or alcohol-resistant foam.
Specific Hazards Arising from the Chemical
Extremely flammable. Gives off irritating or toxic fumes (or gases) in a fire. Vapour/air mixtures are explosive.
Advice for firefighters
Use water in large amounts, alcohol-resistant foam, dry powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 4 | Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Evacuate danger area! Consult an expert! Ventilation. Remove all ignition sources. Remove vapour with fine water spray. Personal protection: complete protective clothing including self-contained breathing apparatus.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Well closed. Separated from strong acids, oxidants, aluminium, copper, copper alloys, zinc, zinc alloys and mercury.
Control parameters
Occupational Exposure limit valuesTLV: 5 ppm as TWA; 15 ppm as STEL.MAK: 4.9 mg/m3, 2 ppm; peak limitation category: I(2); pregnancy risk group: C
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
Information on basic physicochemical properties
- Physical stateLiquid
- ColourColorless
- Odour
no data available
- Melting point/freezing point
10°C(lit.)
- Boiling point or initial boiling point and boiling range
3-4°C(lit.)
- Flammability
no data available
- Lower and upper explosion limit/flammability limit11.6%
- Flash point
-7°C
- Auto-ignition temperature
374°F
- Decomposition temperature
no data available
- pHa strong base (pH 9.8)
- Kinematic viscosity
no data available
- Solubilityvery soluble in water, slightly soluble in alcohol, ether, benzene, toluene, xylene, ethylbenzene, chloroform maximum allowable concentration: TLV 10 p.p.m. (24 mg/m3) and STEL of 15 p.p.m. (36 mg/m3) (ACGIH 1986)
- Partition coefficient n-octanol/water
-0.3
- Vapour pressure430 mm Hg ( 25 °C)
- Density and/or relative density
0.63g/mLat 20°C(lit.)
- Relative vapour density
2.09 (vs air)
- Particle characteristics
no data available
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
The vapour is heavier than air and may travel along the ground; distant ignition possible.The substance is a medium strong base. Reacts violently with mercury and oxidants. This generates fire and explosion hazard. Attacks metals such as aluminium, copper, zinc, tin and their alloys.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
no data available
Acute toxicity
- Oral: no data available
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is corrosive to the eyes and skin. The vapour is severely irritating to the respiratory tract. Corrosive on ingestion.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air will be reached very quickly on evaporation of this substance at 20°C.
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: UN1297 (For reference only, please check.)
IMDG: UN1297 (For reference only, please check.)
IATA: UN1297 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: TRIMETHYLAMINE, AQUEOUS SOLUTION, not more than 50% trimethylamine, by mass (For reference only, please check.)
IMDG: TRIMETHYLAMINE, AQUEOUS SOLUTION, not more than 50% trimethylamine, by mass (For reference only, please check.)
IATA: TRIMETHYLAMINE, AQUEOUS SOLUTION, not more than 50% trimethylamine, by mass (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The toxicological data apply to solutions containing over 15% of trimethylamine.See ICSC 0206 Trimethylamine gas in a cylinder.
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.