(S)-(-)-Propylene oxide
Product identifier
- Product name: (S)-(-)-Propylene oxide
- CBnumber: CB0477536
- CAS: 16088-62-3
- EINECS Number: 240-241-0
- Synonyms: 2-methyloxirane,(S)-2-methyloxirane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: (S)-(-)-Propylene oxide
- Synonyms: 2-methyloxirane,(S)-2-methyloxirane
- CAS: 16088-62-3
- EC number: 240-241-0
- MF: C3H6O
- MW: 58.08
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire. Forms explosive mixtures with air at ambient temperatures.
Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 4 | Will rapidly or completely vaporize at normal atmospheric pressure and temperature, or is readily dispersed in air and will burn readily. Includes pyrophoric substances. Flash point below room temperature at 22.8 °C (73 °F). (e.g. acetylene, propane, hydrogen gas) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Environmental precautions
Do not let product enter drains. Risk of explosion.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb?). Dispose of properly. Clean up affected area.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Advice on safe handling
Work under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Storage conditions
Keep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons.
Refrigerate before opening.
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
control parameter
Hazard composition and occupational exposure limitsExposure controls
Personal protective equipmentUse equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
required
Flame retardant antistatic protective clothing.
required when vapours/aerosols are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type: Filter type AX
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- Appearance liquid
- OdourNo data available
- Odour ThresholdNo data available
- pHNo data available
- Melting point/freezing point-111.9°C
- Initial boiling point and boiling range 33 - 34 °C - lit.
- Flash point-37 °C - c.c.
- Evaporation rateNo data available
- Flammability (solid, gas)No data available
- Upper/lower flammability or explosive limits Upper explosion limit: 37 %(V) Lower explosion limit: 1,9 %(V)
- Vapour pressure 8.59 psi ( 20 °C)
- Vapour density 2 (vs air)
- Relative densityNo data available
- Water solubilityNo data available
- Partition coefficient: n-octanol/waterNo data available
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
No data available
Reactivity
Vapors may form explosive mixture with air.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Heat. Warming.
Incompatible materials
No data available
Hazardous decomposition products
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityRemarks: (racemate)(RTECS)Symptoms: Vomiting, Nausea Symptoms: Shortness of breath, Cough, mucosal irritations
LD50 Dermal - Rabbit - 1.244 mg/kg Remarks: (racemate)
(IUCLID)
Dermal: absorption
Result: Severe irritations Remarks: (RTECS)
Result: Severe irritations Remarks: (racemate) (RTECS)
Risk of corneal clouding.
(racemate) (IUCLID)
Test Type: Mutagenicity (mammal cell test): Result: positive
Remarks: (racemate) (IUCLID)
Toxicity
(IUCLID)
EC50 - Daphnia magna (Water flea) - 350 mg/l - 48 h Remarks: (racemate)
(IUCLID)
Remarks: (racemate) (IUCLID)
Persistence and degradability
Biodegradability Result: 12 - 14 % - Not readily biodegradable.
(OECD Test Guideline 301D)
Bioaccumulative potential
Mobility in soil
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent,
bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
Discharge into the environment must be avoided.
Waste treatment methods
Product
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.
UN number
UN proper shipping name
Transport hazard class(es)
ADR/RID: 3 IMDG: 3 IATA: 3
Packaging group
ADR/RID: I IMDG: I IATA: I
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.