The power of acridine esters is not something we can say clearly in a few words. You may not see it but always touch it invisibly. It is like the star in the vast universe, unremarkable but can illuminate you forward. Especially in medicine, there are so many places where it is used. It seems that it always surprises us wherever it goes, and it becomes so conspicuous again. It has a pale yellow powder appearance, wrapped in a brown bottle, and stored at -20°C in a sealed container.

Acridine esters help diagnosis of hepatitis B

The chemiluminescence quantitative detection kit based on the hepatitis B surface antigen acridinium ester chemiluminescence quantitative immunoassay method can be effectively used in the clinical diagnosis of hepatitis B and the dynamic monitoring of the disease. It has high sensitivity and good specificity, accurate quantification, and all performance indicators It has the advantages of meeting clinical needs, and the price is relatively high acceptability of imported reagents. It has great potential for large-scale clinical application and is of great significance for the prevention and treatment of hepatitis B.

Test of acridinium ester for thyroid hormones

Thyroid-stimulating hormone (TSH) is a glycoprotein hormone secreted by the anterior pituitary gland. Serum TSH level is an important clinical indicator for assessing thyroid function. It needs to be labeled with a certain chemiluminescent reagent during detection. Tracking protein, acridinium ester DMAE-NHS is the most commonly used chemiluminescent reagent.

Application of acridinium ester in immunoassay

Acridinium ester is labeled as a hapten on progesterone to determine the content of progesterone in the plasma of non-pregnant gray females. The detection sensitivity is up to 0.64mol/L. It has a wider scope of application in retaining the biological activity of the traced substance.

Method for labeling nucleic acid DNA with acridine ester

In nucleic acid hybridization analysis, the preparation of labeled probes with strong specificity and high sensitivity is the key to successful nucleic acid hybridization analysis. Acridinium ester derivatives can be directly labeled on nucleic acid probes without the need for catalysts and the luminescence quantum yield is not affected. In addition, under certain conditions, the labeled acridinium ester on the unhybridized single-stranded DNA is hydrolyzed and destroyed, and only the double-stranded protected acridinium ester formed by hybridization can produce chemiluminescence, and the entire hybridization process can be monitored without separation.

Acridine esters method for detecting environmental damage to DNA

Acridine ester can be used as a chemiluminescent indicator with a good intercalation structure of DNA double helix. This detection method is feasible for DNA break damage and chemiluminescence detection method. It has the advantages of simplicity and sensitivity, and provides a simple research method for the research of environmental pollutants on DNA damage.

No matter where the acridinium ester is finally applied, it can always accomplish its task brilliantly. Just like our acridine ester products made by Desheng. Good products always stand the test in any way.