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Hubei xindesheng Material Technology Co., Ltd

Hubei xindesheng Material Technology Co., Ltd

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How to choose heparin in blood collection tube anticoagulant

Release time: 2021-10-28

Recently, many customers often ask us for heparin. There may be people who are not specialists or traders who don’t know what heparin they need. In fact, there are many types of heparin, and different types of heparin are completely different. Even if the main role is to act as an anticoagulant.
The difference in application of different heparins
Heparin is a natural anticoagulant substance in the animal body, and the heparin product after it is extracted can be used in many fields. In terms of application, there are mainly injection-grade heparin drugs in hospitals, heparin, an in vitro anticoagulant used in blood collection tubes or other blood-related experiments, and heparin raw materials used in cosmetics and other products. The prices of these types of heparin are very different. When purchasing heparin, you must figure out the direction of its application, not just the CAS number.
Types of heparin anticoagulants
Heparin products usually exist in the form of salt. The heparin in the animal body (usually pig small intestine, sheep small intestine) is in the form of binding with protein, and it is made into heparin products after extraction, impurity removal, purification, and purification. , Usually heparin sodium, and then made into heparin lithium, heparin calcium, heparin magnesium and other heparin salts.
Heparin Sodium Anticoagulant
Heparin sodium is commonly used in many heparin salt products. Small molecule heparin, enoxaparin, etc. usually belong to this category, which is suitable for the collection and anticoagulation of blood specimens for therapeutic biochemical examinations and emergency biochemical examinations. It is also suitable for blood specimen collection and anticoagulation in some hemorheology projects. It is recommended to use heparin as an anticoagulant when determining the content of ions in the blood in medical tests, because it is the least likely to interfere with the determination of other ions.
Lithium heparin anticoagulant
In addition to heparin sodium, the heparin used for in vitro anticoagulation in blood collection tubes is lithium heparin, which itself is prepared by ion exchange method of heparin sodium, and the cost is slightly higher than that of heparin sodium. The appearance of lithium heparin is white to off-white powder, odorless, easily soluble in water, and easy to absorb moisture. Except for HBD, LDH, and TBA, there is a good correlation between lithium heparin anticoagulated plasma and serum. Therefore, it is more feasible to use lithium heparin anticoagulated plasma instead of serum in biochemical testing, and it can be used as an important testing method.
Heparin sodium and lithium heparin anticoagulants are the two main anticoagulants produced by Desheng, which can be used in vacuum blood collection tubes or some in vitro anticoagulation experiments. Of course, in addition to heparin sodium and heparin lithium, heparin salts such as calcium heparin, potassium heparin, ammonium heparin, and magnesium heparin are also used in the fields of medicine, beauty, and diagnosis.