What is the purpose of blood coagulants?

We talked about many blood collection additives before, such as EDTA dipotassium, tripotassium, disodium, lithium heparin, sodium heparin, sodium citrate, Sodium fluoride, etc. These reagents have one thing in common. They can use different principles of action to prevent blood coagulation within a certain period of time, which is often referred to as blood Anticoagulant. The corresponding of course is blood coagulant, which is an auxiliary reagent in Vacutainer to promote rapid blood coagulation.

There are two common types of coagulants on the market: white suspensions mainly composed of thrombin, alcohol, silica powder, emulsifiers, surfactants, etc; And a white like high-efficiency coagulation promoting powder mainly composed of polymer and coagulation factors.

 

Coagulants are usually used in combination with serum separation gel for rapid extraction of serum samples. Serum separation gel is a layer of gelatinous substance used to separate serum and blood clots, while coagulants quickly coagulate blood and precipitate serum.

Under normal circumstances, blood samples that do not contain blood coagulants will naturally coagulate, but it takes at least an hour for the separated blood to coagulate. Due to the influence of external environment, the phenomenon of non coagulation or partial coagulation often occurs. In order to completely avoid this situation, the use of blood coagulants is particularly important. The application of blood coagulants greatly shortens the time of blood coagulation, improves the efficiency of obtaining high-quality serum samples, and does not affect the test results.

In order to ensure the effectiveness of blood coagulants, special attention should be paid to the following points: when using coagulant suspension, it is important to fully mix the ingredients inside; Excessive or insufficient dosage added to the blood collection vessel can affect the effectiveness of the coagulant; After the final blood collection, it is also necessary to fully fuse the coagulant with the blood sample, in order to achieve better coagulation promoting effect. Desheng specializes in the production of coagulants, and after you purchase the product, professional technical personnel carefully guide you to use it correctly!