Do anticoagulants in blood vessels have a stratification effect on blood?

 

At the hospital's blood testing center, medical staff often process the blood first and then analyze the results on the computer. This approach not only ensures the efficiency of blood testing, but also avoids deviations in the results. The general treatment method for blood samples is to use anticoagulants or coagulants, but it is necessary to distinguish the corresponding testing items, as the blood collection reagents used for different items may vary. Due to the various types of anticoagulant reagents and their frequent use in clinical practice, what effects can they have on the blood? Below, we will focus on introducing it to everyone.

 

1、 Blood status without anticoagulants

Due to the fact that blood contains different cellular components, such as red blood cells, white blood cells, platelets, etc., without anticoagulants after leaving the human body, it will quickly coagulate into a gelatinous form, causing clots to contract. After a period of standing, a faint yellow transparent liquid serum will precipitate around the blood clot. Although it may precipitate, the quality is not high, and there will be no obvious layering effect. The extraction is difficult and difficult to detect.

 

2、 Blood after adding anticoagulants

When anticoagulants are added to the blood collection vessels, once in contact with them, they can have multiple effects on the blood sample:

Preventing blood clotting: Because it can remove or inhibit coagulation factors in blood samples, disrupting the coagulation process from the source, its significant and crucial role is to prevent blood clotting and improve detection efficiency.

 

Layering effect: After adding anticoagulants to the test tube and allowing the blood sample to stand for a period of time, there will be stratification in the blood, which is not very obvious when observed with the naked eye. Through the instrument, it can be seen that the upper layer is plasma, the middle layer is white blood cells and platelets, and the lower layer is red blood cells. This can help to quickly extract the part that needs to be tested.

 

Preservation effect: Due to its ability to prevent blood clotting, it can fully ensure the stability of blood components during storage or transportation, and is not easily affected by external interference in a short period of time. However, it should be noted that the storage time may vary depending on the test items. For example, for general blood routine tests, anticoagulant tubes can be stored for one week under refrigeration conditions, while for biochemical tests, it is recommended that the storage time should not exceed 12 hours.

 

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