What are blood anticoagulants and preservatives?

 

In clinical work, besides blood testing and analysis, the transportation and preservation of blood samples are equally important. If this step is not guaranteed, the test results will inevitably encounter problems. How are blood samples usually preserved? Is there any other reagent to assist? Below, we will provide a detailed introduction to this issue.

 

In fact, when it comes to the preservation of blood samples, anticoagulants exist because with their help, blood samples cannot solidify, and there is no need to worry about not being detected after coagulation during the preservation process, while also ensuring the stability of blood cell components. The two commonly used anticoagulants in transfer preservation are sodium citrate and heparin salt.

 

1、 Sodium citrate

It can chelate with calcium substances in collected blood samples, causing them to lose their reaction during the coagulation process. Among the commonly used anticoagulants for preserving blood samples, it is a commonly used anticoagulant that not only interferes with the coagulation process, but also prevents the occurrence of hemolysis.

 

2、 Heparin salt

As an anticoagulant reagent, it undergoes structural changes by binding to antithrombin, resulting in its ability to bind to various coagulation factors. This prevents coagulation factors from participating in the coagulation process and inhibits the coagulation effect, thus achieving the goal. It is precisely because it can inhibit factors that thrombin like substances can be released for neutralization during the preservation of blood samples, maintaining the stability of blood sample components. However, it is also important to note that the preservation time should not exceed 48 hours.

 

3、 Blood sample preservation solution

This preservation solution not only has anticoagulant effects, but also has the ability to protect the survival of blood cells. Its main components are sodium citrate, glucose, phosphate, and adenine. According to the differences in formula, it is divided into two categories: ACD solution and CPD solution. The use of this preservation solution can effectively extend the shelf life of red blood cells, enhance their oxygen release function, and prevent hemolysis from occurring. Although it is a favorable solution for blood preservation, it is not without a deadline, and testing must generally be completed within about 20 days. If there are special requirements for platelets, it should also be noted that the storage temperature should be around 22 degrees Celsius, and the surrounding temperature should not be too high.

 

As a raw material manufacturer of blood vessel additives, Desheng has always pursued quality as the top priority, from research and development to production, sales, and interlocking, with strict supervision and control by dedicated personnel. At present, the products of serum separation gel, heparin salt, and EDTA potassium salt have received unanimous praise and high turnover rate. If you are interested, please click on the website to inquire and purchase!