Which is more suitable for blood sugar testing, sodium fluoride anticoagulant tubes or separation gel anticoagulant tubes?

 

Nowadays, with the improvement of material life, people eat more and more food, and lack of exercise, mental stress, high blood sugar and diabetes incidence rate is also increasing year by year. Blood sugar, as an important indicator of physical disease, directly determines the diagnosis and treatment of patients with the accuracy of its results. Therefore, conducting blood sugar tests in clinical work has become increasingly common. At present, sodium fluoride anticoagulant tubes and separation gel anticoagulant tubes are generally used for analysis in blood glucose testing. However, they are not used together, but one of them is chosen for use. However, the question arises, which one is more suitable for blood glucose testing? Let's take a look together.

 

1、 The Effect of Sodium Fluoride Anticoagulant Tube and Separation Gel Anticoagulant Tube

Sodium fluoride anticoagulant tubes mainly prevent glycolysis by inhibiting the enolase in glycolysis through F -, while separation gel anticoagulant tubes use inert separation gel substances to achieve the goal. Due to its special specific gravity, it can be intermediate between serum and blood clots, ensuring that there is no material exchange between the two, which can effectively extract the necessary parts in blood sugar analysis. Although the two mechanisms of action are different, both can process blood to complete blood glucose testing.

 

2、 Experimental results of sodium fluoride anticoagulant tubes and separation gel anticoagulant tubes

Although both can complete blood sugar testing, from the experimental results, it can be seen that the blood sugar indicators measured by the separation gel anticoagulant tube are actually higher than those measured by sodium fluoride, which is roughly related to the anticoagulant in the sodium fluoride tube. Compared with the separation tube, the anticoagulant agent sprayed in the sodium fluoride tube may have a certain dilution effect on the collected blood, which will affect the measured blood sugar to be lower than the actual results. Therefore, in order to make the blood sugar measured by the sodium fluoride tube closer to the accurate value, the amount of blood sample collection can be increased, which will reduce the impact on diluting the blood.

 

3、 Which is more suitable for blood sugar testing, sodium fluoride anticoagulant tubes or separation gel anticoagulant tubes?

Due to the different roles played by the two, it can be observed in the experiment that there is no change in the behavior of serum or plasma in the separation tube, while using sodium fluoride tube will change the original substances in the serum. Although it can inhibit glycolysis and is basically not affected by hemolysis, uric acid, or other drugs, and has high accuracy and precision, small details of deviation cannot be ignored. In practical operation, the method of controlling blood sugar is unstable, and if some original substances in the serum are changed, the results will also be affected. So from this perspective, the separation tube is more suitable for blood glucose detection, but sometimes suitable test tubes are selected based on experimental requirements. Generally, it varies from person to person and can be flexibly selected and used.

 

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