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Is anticoagulant a factor affecting the results of blood gas analysis?
Release time: 2023-02-16
Is anticoagulant a factor affecting the results of blood gas analysis?
With the development of medical technology, the appearance of blood gas analyzer has gradually become an indispensable equipment in clinical detection, which provides extremely important help for the diagnosis, treatment and prognosis of patients. However, because of the continuous metabolism of blood cells and the instability of gas, the test results will be affected by a variety of factors. If the influencing factors cannot be understood, it may lead to the wrong judgment of the disease in the later stage and affect the diagnosis and treatment work.
There are different opinions on the factors affecting the blood gas analysis results on the Internet. Some people think it is caused by the use of anticoagulants, and some people think it is caused by improper operation. Are these factors? In fact, it has a certain relationship with these aspects, but it is not a decisive factor. Let me give you a detailed analysis.
1、 Effect of anticoagulant on test results
There are many types of anticoagulants, such as EDTA, sodium citrate, potassium oxalate, heparin, etc., but the first three anticoagulants will cause changes in pH value and decrease in Ca2+detection results in blood gas analysis, so it is necessary to select appropriate anticoagulants for use, usually heparin sodium or heparin lithium.
Although heparin is an ideal choice, we should also pay attention to whether to use ordinary heparin or refined heparin. Ordinary heparin products may lead to false measurement results. In medicine, it is recommended to use refined heparin lithium tube to collect samples, which has the advantages of good anticoagulation effect, and does not combine electrolyte, and the sample will not be diluted. Therefore, from the perspective of anticoagulant, it is not the decisive factor that results in inaccurate blood gas analysis. As long as the anticoagulant that meets the requirements is selected, it will not have adverse effects.
2、 Influence of sample storage and transportation on test results
In addition to anticoagulants, there is also the impact of storage and transportation. Because blood cells will react outside the body during the collection process, the glycolysis process will lead to oxygen consumption and carbon dioxide generation, which will affect the relevant detection values. So after collecting blood samples, they will be sealed and placed in the water bath for examination immediately. If they are not sent for examination in time or directly contacted with the ice bag, it will have a direct impact on the results.
3、 Influence of operation process on test results
After collecting blood samples, the standard test time is usually within 30 minutes, and the operator is required to gently roll the test tube and mix it upside down for at least 30 seconds before testing. At the same time, it should be noted that the blood in the collector is easy to coagulate, and two drops should be dropped before testing to prevent the sample from blocking the needle and prevent the sample from being unable to suck. If the operator makes an error in this process, the result will be inaccurate.
Desheng, as the manufacturer of anticoagulant, has a complete range of products. According to the requirements of the test items, it can provide different anticoagulant products with stable performance, which are all in powder form, ensuring that the products are not damaged during transportation and convenient for customers to use. Interested parties are welcome to click the website for details!