TOOS is a good helper for the detection of glycosylated serum albumin

 

Glycated serum albumin is an early glycosylation product produced by the non-enzymatic glycosylation reaction between albumin and glucose in the blood. It is generally believed that the determination of glycosylated serum albumin can accurately reflect the blood glucose control of human body for 2-3 weeks. A large number of studies have shown that the detection of glycosylated serum albumin has a good effect on the therapeutic effect and clinical dosage of diabetes, so the use of glycosylated serum albumin detection kit is very necessary.

 

TOOS as a chromogenic substrate plays an important role in the glycosylated serum albumin detection kit. Its working principle is to use glucose oxidase to catalyze the oxidation of glucose to generate hydrogen peroxide, and platinum bismuth nano-simulated peroxidase to catalyze the coupling reaction between MBTH and the chromogenic substrate TOOS, showing purple product solution. With the increase of glucose concentration, the color of the solution deepens, and the maximum absorption wavelength of the chromogenic system is 590nm, The content of glucose can be obtained from the absorbance at 590 nm.

 

The wide application of glycosylated serum albumin test kit reduces the cost of diagnosis and detection, and has the characteristics of high accuracy and stability. As an early glycosylation product in patients with diabetes, glycosylated albumin can destroy the function of endothelial cells, lead to oxidative stress and inflammatory reaction of vascular wall, stimulate the proliferation and migration of smooth muscle cells, and these pathological processes will lead to the formation and development of atherosclerosis and diabetes vascular complications. Therefore, glycosylated serum albumin has become one of the important blood glucose indicators in clinical practice.

 

Hubei Xindesheng Material Technology Co., Ltd. specializes in the production of new and new Trinder's reagents. In addition to TOOS, there are also TOPS, ADOS, ADPS, etc. After more than ten years of intensive research and development, the technology of producing new Trinder's reagent has been very mature, and the products have also been exported to foreign countries. At present, there are more than 400 large, medium and small new enterprises at home and abroad cooperating with Desheng, and their products and services are widely recognized by users. If you are also interested in the new Trinder's reagent, please click the official website for consultation and look forward to communicating with you!