Detection of blood glucose and liver function with chromogenic substrate TOOS

 

There are many kinds of chromogenic substrate reagents for in vitro diagnosis, and the traditional chromogenic substrate is TMB. Today we are going to talk about TOOS reagent, which is one of the new Trinder's reagents developed by taking the essence from the original chromogenic substrate products and removing the dregs. It is well known that the new Trinder's reagent has many advantages as an in vitro diagnostic reagent, while TOOS, as one of the series of products, can not be underestimated. This article will introduce its advantages in the detection of blood sugar and liver function.

 

First of all, the reaction principle of TOOS is introduced. Like other Trinder reagents, the principle is that the hydrogen peroxide produced by the detected substance under the interference of enzyme will produce red compounds under the influence of 4-aminoantipyrine and peroxidase. This reaction is called coupling end colorimetry. This feature can be used in the early diagnosis of some diseases.

 

1. TOOS for blood glucose detection

TOOS is mainly used to prepare glucose detection reagent and glycosylated albumin detection reagent, and is an important reagent in the blood glucose metabolism project. When used, the color of the color product solution of TOOS is purple. With the increase of glucose concentration, the color of the solution will also change. The maximum absorption wavelength of the color system is 590 nm, and the glucose content can be obtained from the absorbance at 590 nm.

 

2. TOOS for routine detection of liver function

TOOS is one of the main components of adenosine deaminase detection reagent, which will be used in the routine examination of liver function. It can reflect the sensitive indicators of liver injury and provide reliable data. TOOS has good color rendering effect, fast response and high precision, which makes the data it detects more authoritative.

 

Desheng is a manufacturer of new Trinder's reagents, which can provide a series of reagents such as TOOS. It is independently developed and produced, with small difference between batches and sensitive response, and has important value in clinical diagnosis. If you need to purchase, please feel free to contact us for consultation and order!