Don't mix up EDTA dipotassium and EDTA disodium

 

Both potassium EDTA and disodium EDTA are additives in evacuated blood collection vessels, which are used for anticoagulation. Its action principle is to influence the coagulation function of calcium ions by chelating with calcium ions in blood samples, thus preventing blood coagulation. From the appearance, both potassium EDTA and disodium EDTA are white crystalline powders, which are easily soluble in water and need to be sealed for storage.

 

Although both potassium EDTA and sodium EDTA can be used as anticoagulants with similar names, there are still some differences in use and characteristics:

 

1. Physical properties

Dipotassium EDTA can be slightly soluble in alcohol. After it is prepared as an aqueous solution, the pH value is about 4.0-5.0 at room temperature of 20 ℃. However, disodium EDTA is hardly soluble in alcohol. After it is prepared as an aqueous solution, the pH value is about 4.0-6.0 at room temperature of 20 ℃.

 

2. Use of blood anticoagulation

EDTA dipotassium has a certain protective effect on blood cells and has little effect on red blood cells, so it does not affect the count of white blood cells and red blood cells, and can inhibit platelet aggregation to a certain extent. The blood anticoagulation function of disodium is similar to that of dipotassium, but the solubility of disodium is obviously lower than that of dipotassium, which will affect the anticoagulation effect when used.

 

3. Other purposes

EDTA disodium is more widely used. In addition to being used as an additive for blood collection, it is also a food additive that is often added to canned sugar, and it can also be used as a bleaching fixer, dyeing aid, fiber treatment agent, etc. for the processing of color sensitive materials. In addition to being an anticoagulant, potassium EDTA can also be used to prepare toilet deodorant, metal polishing agent and complexing agent in liquid phase analysis.

 

Hubei Xindesheng Material Science and Technology Co., Ltd. can produce both EDTA potassium and EDTA sodium. After more than ten years of hard research, the company has a professional research and development team to produce a series of additives for vacuum blood collection. In addition to potassium, sodium and potassium, EDTA series also produces serum separating gel, sodium heparin, lithium heparin, silicating agent and coagulant. If you are interested, Click the official website for consultation now!