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Sodium citrate as a blood collection additive
Release time: 2023-01-06
Sodium citrate as a blood collection additive
Sodium citrate, also known as sodium citrate, is a common anticoagulant in vacuum blood collection vessels. Its appearance is white powder crystal. Its anticoagulation principle is that citrate ions in sodium citrate chelate with calcium ions in blood samples, thus affecting the coagulation effect of calcium ions on blood.
There are two kinds of vacuum blood collection tubes with sodium citrate added as anticoagulant. One is the blue cap vacuum blood collection tube used for blood coagulation measurement. The concentration of sodium citrate is 3.2% or 3.8%, that is, 0.109mol/L or 0.129mol/L. When using this vacuum blood collection tube, the ratio of sodium citrate to blood sample is 1:9.
The other is a brown cap vacuum blood collection tube for ESR measurement. The concentration of sodium citrate added to the tube is 3.2%, which is equivalent to 0.109mol/L. The ratio of sodium citrate to blood required by this tube collection is 1:4. The volume of blood sample of the two kinds of evacuated blood collection vessels is 2ml.
When using the vacuum blood collection tube with sodium citrate, after obtaining the blood sample, it is necessary to gently reverse the blood sample and anticoagulant fully and evenly to fully avoid blood coagulation. If it is ESR test, it can be directly put on the ESR rack. If it is hemagglutination test, it needs to obtain the upper plasma through centrifugation for testing.
However, due to the strong alkalinity of sodium citrate and its weak anticoagulant effect, the scope of use is very limited. Because citrate and calcium ions can form soluble complexes, sodium citrate is usually used as an anticoagulant or blood transfusion agent, which has a good effect on the preservation and processing of blood products.
Hubei Xindesheng Material Technology Co., Ltd. has been specializing in the research, development, production and sales of blood collection additives for 18 years, with a deep research and development background and professional technicians. At this stage, we have independently developed a full set of blood collection additives, such as anti irradiation serum gel, heparin sodium, heparin lithium and other anticoagulants, high efficiency coagulating powder and coagulant accelerator. Siliconizing agent has been sold to many regions at home and abroad, and has won praise from many customers. If you are also interested, click the official website to inquire!