Do you really know whether heparin sodium is an anticoagulant or a coagulant accelerator?

 

In recent years, the progress of medicine has changed the traditional way of blood collection and improved the collection efficiency. Half of the credit belongs to blood collection additives, such as serum separating gel, coagulant accelerator, anticoagulant, etc. Because of their performance, they can help doctors and nurses make more accurate judgments.

 

As anticoagulants and coagulants are widely used in clinical practice, they contain many types of products. For example, anticoagulants include heparin sodium, heparin lithium, EDTA potassium salt, etc. Many people may be confused or confused, so here we will focus on introducing heparin sodium. Is it a coagulant or an anticoagulant?

 

Effect of heparin sodium

 

Because heparin is extracted from pig intestinal mucosa, it can interfere with the coagulation process, and because it has the function of preventing platelet aggregation and inactivating thrombin, it can play an anticoagulant role, so it can be known from this role that heparin sodium is an anticoagulant, not a coagulant.

 

Types of heparin sodium

 

Since there are many types of heparin sodium, it is necessary to know clearly which type it belongs to as an anticoagulant.

 

1. Crude heparin sodium: it is directly extracted and processed from animal liver, and generally presents yellow powder. Although it also has anticoagulant function, crude heparin is not the first choice, with low requirements, and generally can be used for other purposes.

 

2. Heparin sodium for external use: it is mainly extracted from the small intestinal mucosa of pigs, but it needs further extraction and processing, and it needs to ensure stable process, molecular weight and potency. Therefore, most people will choose this heparin sodium for use as an external anticoagulant in blood collection.

 

3. Injectable heparin sodium: this kind of heparin sodium is directly injected into the human body to prevent thrombotic diseases, such as myocardial infarction, and usually does not use anticoagulant type heparin sodium raw materials.

 

Precautions for extraction of heparin sodium as anticoagulant

 

Because some groups in heparin have a great impact on anticoagulant activity, it is necessary to pay special attention to the preparation of anticoagulants in acid and alkaline solutions, which are easy to hydrolyze and be damaged, leading to reduced anticoagulant activity. In the production process of heparin sodium, it is necessary to avoid treatment with strong acid or strong base.

 

Desheng Biochemical is a professional supplier of heparin sodium. No matter in research and development or production and sales, it does it by itself without any third-party involvement, so it has more advantages in product quality and price than other businesses. At present, the number of enterprises supplied has reached more than one hundred, and they have received continuous praise. If you have relevant needs, please click the website or call for consultation!