Heparin Sodium or Heparin Lithium? This is a question

Heparin is an acidic mucopolysaccharide, which was first discovered in the liver, hence named as heparin, mainly produced by mast cells and basophils, and now mainly extracted from bovine lung or pig small intestinal mucosa. Heparin has physical and chemical properties with a strong negative charge, can interfere with many links in the blood coagulation process, and has anticoagulant effects both in vivo and in vitro, and its mechanism of action is very complicated. Heparin has a strong anticoagulant effect.

The pharmacological effect of heparin as an anticoagulant has the following aspects. First, heparin can enhance the affinity between antithrombinIIIand thrombin and accelerate the inactivation of thrombin.Secondly, it can inhibit the adhesion and aggregation of platelets.Finally, it can enhance the protein C.The activity of vascular endothelial cells is stimulated to release anticoagulant substances and fibrinolytic substances.

Heparin is the only anticoagulant that can be used for the determination of pH, blood gases, electrolytes and calcium ions. When heparin is added to the blood collection tube, it directly has the effect of antithrombin, which can prolong the coagulation time of the specimen. It is suitable for red blood cell fragility test, blood gas analysis, red blood cell extrusion test, erythrocyte sedimentation rate and general energy biochemical determination, but not suitable for blood coagulation experiment. Excessive heparin will cause great changes in white blood cells, so it cannot be used for counting white blood cells.

As the most commonly added heparin sodium and heparin lithium in blood collection tubes, how should we choose? Lithium heparin and sodium heparin are both a binding form of heparin, but the effective ion binding is not the same, so there are great differences in the degree of dissociation. Through experimental comparison, the effect of heparin lithium is better than that of heparin sodium, so the usage and measurement of heparin sodium and heparin lithium in vacuum blood collection tubes are different, so as price.

Desheng Biochemical is a manufacturer specializing in the production of heparin sodium and heparin lithium. Many customers highly recognize the quality of its products and repurchase them for a long time. The company also provides customers with one-stop purchasing services and professional services. And questions can be solved immediately.Heparin sodium and heparin lithium can be chosen according to your actual requirements. Welcome to click on the website for inquiry!