Differences in the application of disodium EDTA, dipotassium EDTA and tripotassium EDTA in vacuum blood collection tubes

The EDTA disodium, EDTA dipotassium and EDTA tripotassium used in the vacuum blood collection tubes are all of analytical grade, and can be combined with calcium ions to form a chelate to play an anticoagulant effect, but few people know the difference between them. Now follow the editor to understand the difference between them.

Disodium EDTA refers to disodium ethylenediaminetetraacetic acid, which is white crystalline particles or powder, odorless, tasteless, soluble in water, and extremely insoluble in ethanol, with a pH value of 5.5. However, the solubility of disodium EDTA is lower than that of dipotassium, so relatively speaking, there will be more customers purchasing dipotassium.

While dipotassium EDTA refers to dipotassium ethylenediaminetetraacetate, which is a white crystalline powder, odorless, easily soluble in water, and easy to absorb moisture, with a pH value of 4.8. In a spray-dried state, it can protect the cellular components of blood, does not affect white blood cell count and size, has minimal effect on red blood cell morphology, and can inhibit platelet aggregation, and is often used for blood cell counts. 

Tripotassium EDTA refers to tripotassium ethylenediaminetetraacetate, which is also a white powder. It has one more potassium ion than dipotassium EDTA, but it is more delicate than dipotassium EDTA, and the effect of dissolving in water will be better, but it is suitable for The range is relatively narrow. When used as a blood collection tube additive, the analytically pure grade EDTA tripotassium is in a liquid state in the glass tube blood collection tube, and the plastic tube blood collection tube is in a spray-dried state, and when detecting red blood cells, when the concentration reaches 7.5mg/ml , shrinkage occurs.

Hubei New Desheng Material Technology Co., Ltd. specializes in R&D, production and sales of analytically pure grades of disodium, dipotassium and tripotassium EDTA for 17 years. It strictly controls the quality of products and can supply blood collection tube additives with stable quality for a long time. So far, the products have been widely used by more than 150 manufacturers at home and abroad. If you have relevant needs, you can go to the official website or call for consultation.