In serum testing, coagulants can be selected to rapidly coagulate blood, while in whole blood or plasma testing, different anticoagulants are selected to prevent coagulation of collected venous blood.What are the commonly used anticoagulants? Hubei Xindesheng Materials Co., Ltd. has compiled some points of anticoagulants for us.

Citrate

The anticoagulation principle of citrate is forming a chelate with calcium ions in the blood to prevent blood coagulation,such as sodium citrate.The color of citrate blood collection tubes are blue or black head.The ratio of anticoagulant to blood in the blue head tube is 1:9 and in the black head tube is 1:4.The blue-headed tube is often used for determinations of blood coagulation,and the black-headed tube is used for erythrocyte sedimentation rate.

EDTA

The anticoagulation principle of EDTA is forming chelate with calcium ions in the blood to prevent blood coagulation such as EDTA-K2.The head of EDTA tubes are in purple.It normally used in blood routine examination, blood cell morphology examination.

Oxalate

The anticoagulation principle is oxalate reacts with calcium ions to form calcium oxalate precipitation, thereby preventing blood coagulation. Such as sodium oxalate, ammonium oxalate, etc.The head of oxalate tubes are in gray.It is often mixed with sodium fluoride which can inhibit glucose glycolysis for blood glucose determination.

Heparin

Heparin is a physiological anticoagulant which widely present in human tissues such as liver and lung. It takes effect by enhancing the activity of antithrombin III (AT-III), inactivating serine protease and preventing the formation of thrombin,  such as lithium heparin, sodium heparin, etc.The head of heparin tubes are in green.It normally used in various biochemical tests.

In addition, Wuhan Desheng Biochemical Technology Co., Ltd. is a professional blood test reagents in research and development, production and sales. We are an established company specializing in the production of anticoagulant raw materials used in blood collection tubes, including sodium heparin, lithium heparin, dipotassium EDTA, tripotassium EDTA, disodium EDTA, potassium oxalate, trisodium citrate, sodium fluoride, etc.Welcome your consultation.