Coagulant is a common additive for blood collection tubes. It is also called a suspending agent. It can be made into vacuum blood collection tubes and injection blood collection tubes. It has the function of quickly promoting blood coagulation and is commonly used in clinical biochemical testing. Blood coagulant is composed of thrombin, alcohol, silica powder, emulsifier, surfactant and so on. Its appearance is a white suspended liquid with a faint smell of organic solvents, which is non-toxic and harmless.
How to use coagulant:
Machine spraying or manual adding method can be used. During the adding process, keep stirring to keep the suspension uniform. You can use the machine to stir. After stirring and adding, it can be used after 40-800℃ hot air drying. 20-30ul of coagulant It can quickly promote coagulation of 2-5ml of blood at 20-25°C.
Precautions for the use of coagulant:
When the blood sampling environment temperature is lower than 20°C, in addition to appropriately increasing the amount of coagulant added, the number of inversions and mixing should be increased to prolong the clotting time. If rapid detection is required, it can be better to use a 36°C water bath.
Insufficient coagulation will cause blood cells and fibrin filaments to hang up and mild hemolysis. The coagulation process may stop, or there may be no serum separation after centrifugation.
After blood collection, if the blood and the coagulant are not fully fused and centrifuged, it is easy to form fibrin jelly-like coagulation or fibrin filaments whose specific gravity is smaller than that of blood clots, so they remain in the serum layer and partially adhere to the separation gel. At this time, directly on the machine can cause blockage of the automatic analysis blood sampling needle.
After opening the coagulant, it needs to be sealed and stored, below 4°C, and used up within 7 days.
It is forbidden to use it when it is found that there are impurities and foreign bodies in the coagulant with abnormal odor, abnormal color and expiration date.
The coagulant is an organic solvent liquid, flammable, has slight anesthetic properties, and is non-toxic. If it gets on the skin, wash it off with water.
Desheng company specializes in the production of blood collection tube additives. It has been more than ten years since the establishment of the company. The main products produced and operated include: coagulant, coagulation powder, serum separation gel, heparin sodium, heparin lithium, EDTA dipotassium/ We have a professional team to manage R&D and production of tripotassium, etc. If you are interested in Desheng's products, you can enter the company's official website to contact customer service for more information.