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XANTHOHUMOL
Release time: 2023-01-04
XANTHOHUMOL
|
Product Name: |
XANTHOHUMOL |
|
Synonyms: |
XANTHOHUMOL;XANTHOHUMOL, HUMULUS LU PULUS;2′,4′,4-TRIHYDROXY-6′-METHOXY-3′-PRENYLCHALCONE;(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one;XanthohuMo;Xanthohumol from hop (Humulus lupulus);1-(2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one;2-Propen-1-one,1-[2,4-dihydroxy-6-Methoxy-3-(3-Methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-,(2E)- |
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CAS: |
6754-58-1 |
|
MF: |
C21H22O5 |
|
MW: |
354.4 |
Xanthohumol (6754-58-1) binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation and resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II)1. Impairs prostate cancer cell growth and proliferation2. Cell permeable.
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