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Pharmacology of corosolic acid
Release time: 2022-11-22
In vivo and in vitro experiments showed that corosolic acid promoted the absorption and utilization of glucose by stimulating glucose transport, thus achieving its hypoglycemic effect. Corosolic acid's excitatory effect on glucose transport is similar to that of insulin; therefore, corosolic acid is also known as plant insulin.
The results of animal experiments showed that corosolic acid had a significant hypoglycemic effect on both normal rats and hereditary diabetic mice. Corosolic acid also has a weight loss effect. Clinical studies have found that after taking this drug, it can regulate insulin and blood sugar content in the body, and has a significant weight loss trend (monthly average weight loss of 0.908-1.816Kg).
The process is relatively slow and there is no need to diet. Corosolic acid also has a variety of other biological activities, for example, it has a significant inhibitory effect on TPA-induced inflammation, and its anti-inflammatory effect is stronger than that of the commercially available anti-inflammatory drug indomethacin. It also has the activity of DNA polymerase inhibition, and has the inhibitory effect on the growth of various tumor cells.
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