1. Effects on the heart 0.2g of alcohol precipitation solution from Eucommia ulmoides leaves can significantly increase coronary blood flow in isolated guinea pig hearts. In rabbits, intravenous injection of 20g/kg had no adverse effect on ST segment elevation and T wave changes induced by intravenous isoproterenol.

2. 2, Antihypertensive effect anesthesia dogs and cats after intravenous injection of Eucommia Ulmoides leaf decoction 0.4g/kg, blood pressure rapidly decreased, maintained for 5 minutes and then gradually recovered; The blood pressure decreased significantly when the dose was above 1g/kg, which could be maintained for a long time. Alcohol extract also has antihypertensive effect, but the antihypertensive range and maintenance time are worse than water decoction. The antihypertensive tests of anaesthetic dogs and cats have proved that repeated intravenous administration of Eucommia ulmoides leaf decoction and alcohol extract in a short period of time can produce rapid tolerance phenomenon, and even no antihypertensive effect can be found after 3-4 consecutive administration. Water decoction of Eucommia ulmoides leaves and 65% ethanol extract at 6g/kg could significantly reduce blood pressure in rabbits. The aqueous solution, alcohol solution, ether solution and purified components of Eucommia ulmoides leaves, such as sugars, alkaloids, peach leaf corallin and chlorogenic acid, all had different degrees of hypotensive effect when injected to rabbits.

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