About fisetin:
Smoke Tree Extract Fisetin is a flavonol, a structurally distinct chemical substance that belongs to the flavonoid group of polyphenols. It can be found in many plants, where it serves as a colouring agent. Its chemical formula was first described by Austrian chemist Josef Herzig in 1891. Fisetin can be found in various plants such as Acacia greggii, Acacia berlandieri,in the yellow dye young fustic from Rhus cotinus (Eurasian smoketree), in Butea frondosa (parrot tree), Gleditschia triacanthos, Quebracho colorado and the genus Rhus and in Callitropsis nootkatensis (yellow cypresses). It is also reported in mangoes.
Staherb Fisetin main function:
1. Fisetin can be used to cure rheumatism, dysentery, gastrological, hernia, abdominal distension, toothache, traumatic injures, and skin ulcer in clinical.
2. Fisetin can anti-inflammatory.
3. Fisetin can antiproliferative.
4. Fisetin can indications Rheumatoid arthritis, diarrhea, stomach pain, hernia pain,
abdominal distention, pain, bruises, swelling, sores, carbuncles.
5. Fisetin can dispeling wind and dehumidify.
Staherb Fisetin Application:
1. Applied in food field, Fisetin powder is a kind of nourishing food which has much benefits to brain;
2. Applied in pharmaceutical field, Fisetin powder can be used to treat coronary heart disease and has better effect;
3. Applied in cosmetic field, Fisetin powder owns the function of whitening, dispelling spot, anti-wrinkle, and activating skin cells.
For more prouct information pls contact email sales09@staherb.cn
Physical index:
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analysis
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Specification
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Result
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Test method
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Physical Description
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Appearance
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Yellow powder
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Complies
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Visual
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Odor
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Characteristic
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Characteristic
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Organoleptic
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Sieve Analysis
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100% pass 80 mesh
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Complies
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80 mesh
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Chemical Tests
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Assay ( Fisetin )
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98.0% Min
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98.26%
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HPLC
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Loss on drying
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5.0% Max
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2.33%
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5g/105℃/2hrs
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Bulk Density
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45-60g/100mL
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Complies
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/
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Microbiology Control
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Total plate count
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1,000cfu/g Max
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Complies
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AOAC
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Yeast & Mold
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100cfu/g Max
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Complies
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AOAC
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E. Coli
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Negative
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Negative
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AOAC
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Salmonella
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Negative
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Negative
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AOAC
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Conclusion
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Complies with the standards.
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General Status
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Non-GMO, Non-irradiation, ISO & Kosher Certificated.
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Packing and Storage
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Packing: Pack in paper-carton and two plastic-bags inside.
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Shelf life: 2 year when properly stored.
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Storage: Store in a well-closed place with constant low temperature and no direct sun light.
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Determination of Fisetin
Determination of Fisetin in Smoke Tree P.E. by HPLC
HPLC Conditions:
Column: Inertsil ODS-3 4.6×150mm 5μm
Flow rate: 1.0 mL/min
Detection wavelength: 368 nm
Mobile phase: Acetomitrile: water: phosphoric acid (23:77: 0.1, V/V)
Sensitivity: 0.01AUFS
Column Temperature: 25 ℃
Injection Volume: 10μl
Solution Preparation
1. Standard Preparation:
Accurately weigh approximately 3mg of Fisetin Standard into a 25ml volumetric flask. Dilute to volume with methanol.
2. Sample Preparation:
Accurately weigh approximately 10mg of Smoke Tree P.E. and transfer into a 50ml volumetric flask. Add a 30ml methanol and sonicate for 30min. After cool at room temperature and dilute to volume with methanol. Filter through a 0.45μm filter into an HPLC vial or centrifuge to obtain a clear test solution.
III. Calculation
Under the above chromatographic conditions, when the instrument is stable, and the sample was measured at baseline.
The retention time of Fisetin is about 20 min. The final results are quantified against external standard.
