Corosolic acid has become a popular product in the market as a new plant medicine and a functional natural health food for the prevention and treatment of obesity and type II diabetes;The natural product is currently being marketed as a nutritional supplement in the United States and is currently undergoing Phase 3 clinical trials for the treatment of diabetes, and will soon be approved by the FDA;Compared with insulin injection in the treatment of diabetes, it has significant oral effect, less toxic side effects, easy to use and other advantages, the effect is comparable to insulin injection.
The content of corosolic acid in plants is generally very low, and even the content of corosolic acid is only about 0.01% in the concentrated extract extracted from the hot water of Crapesmus macrofloris;In the concentrated alcohol extract of Barnabas leaf, the content of corosolic acid is only about 1%;After years of research, Microherb has successfully isolated high-purity 98% corosolic acid by advanced chromatographic separation technology, which is used in efficacy and toxicity experimental and clinical studies for the prevention and treatment of obesity and type II diabetes.