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The Strongest Analgesic Effect of Incarvillea Ester Alkali
Release time: 2022-03-27
Incarvillea sinensis extract was introduced in June 2016 can be used as the development of new type of important leading compounds in the treatment of neuropathic pain or drug candidates, incarvillea ester base has become a key leading compounds of narcotic powerful analgesic drug development. Incarvillea ester alkali is analgesia of incarvillea active ingredient, with novel and unique chemical structure, is expected to become an important lead compounds to develop new analgesic drugs.
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Incarvillea sinensis extract was used by Jia Yanxing team to develop a good preparation of incarvillea ester alkali and its structural analogs method, and systematically studies the analgesic activity, they find incarvillea ester alkali and its two structural analogues, on sexual nerve injury model of rats with formalin model, than the current treatment of neuralgia effect is the best drug gabapentin effect is better. These three kinds of compounds in 20 milligrams per kilogram of body weight using the curative effect of or 40 mg per kilogram of body weight and use 100 mg of gabapentin. As a result, experts believe that the three compounds can be used as a development of new type of important leading compounds in the treatment of neuropathic pain or drug candidates, deserves further research and development.