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Life sciences

Life sciences

IF:5.2 CiteScore:12.1999 Articles:841
Life Sciences is an international journal publishing articles that emphasize the molecular, cellular, and functional basis of therapy. The journal emphasizes the understanding of mechanism that is relevant to all aspects of human disease and translation to patients. All articles are rigorously reviewed. The Journal favors publication of full-length papers where modern scientific technologies are used to explain molecular, cellular and physiological mechanisms. Articles that merely report observations are rarely accepted. Recommendations from the Declaration of Helsinki or NIH guidelines for care and use of laboratory animals must be adhered to. Articles should be written at a level accessible to readers who are non-specialists in the topic of the article themselves, but who are interested in the research. The Journal welcomes reviews on topics of wide interest to investigators in the life sciences. We particularly encourage submission of brief, focused reviews containing high-quality artwork and require the use of mechanistic summary diagrams.

Nitazoxanide alleviates experimental pulmonary fibrosis by inhibiting the development of cellular senescence

Published: 9 December 2024 DOI: 10.1016/j.lfs.2024.123302
Xianzhe Wang,?Yanyan Zhu,?Huilin Liu,?Xiangchuan Wang,?Hongjie Zhang,?Xiuping Chen

Aerobic exercise training attenuates ischemia-reperfusion injury in mice by decreasing the methylation level of METTL3-associated m6A RNA in cardiomyocytes

Published: 5 December 2024 DOI: 10.1016/j.lfs.2024.123294
Xinmin Zhang,?Dong-Xu Huang,?Chengluan Xuan,?Yanhui Li,?Yuting Jiang,?Xuehan Wu,?Wenqian Zhou,?Yang Lei,?Fan Yang,?Haichun Ma,?Kun Hou,?Xue Han,?Guichen Li

The modulation of cholecystokinin receptor 1 in the NAc core input from VTA on METH-induced CPP acquisition

Published: 3 December 2024 DOI: 10.1016/j.lfs.2024.123290
Jian Wang,?Minglong Zhang,?Yufei Sun,?Xiaorui Su,?Rongji Hui,?Ludi Zhang,?Bing Xie,?Bin Cong,?Yixiao Luo,?Di Wen,?Chunling Ma

L-Histidine attenuates NEFA-induced inflammatory responses by suppressing Gab2 expression

Published: 4 May 2024 DOI: 10.1016/j.lfs.2024.122672
Mengze Li , Huiying Wang , Hanjun Ren , Tao Zhang , Guoyan Zhou , Shiyi Chen , Jie Wang , Xianbo Jia , Songjia Lai , Xiang Gan , Wenqiang Sun

Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms

Published: 1 September 2022 DOI: 10.1016/j.lfs.2022.120728
Elham Ramazani , Maryam Akaberi , Seyed Ahmad Emami , Zahra Tayarani-Najaran

Pretreatment of CD-1 mice with 4-methylpyrazole blocks toxicity from the gamma-hydroxybutyrate precursor, 1,4-butanediol

Published: 5 July 2002 DOI: 10.1016/S0024-3205(02)01744-7
L.S Quang , M.W Shannon , A.D Woolf , M.C Desai , T.J Maher

Analysis of isethionic acid in mammalian tissues

Published: 15 June 1977 DOI: 10.1016/0024-3205(77)90182-5
Mohamed A. Remtulla, Derek A. Applegarth, Donald G. Clark, Ian H. Williams