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Clinical Cancer Research

Clinical Cancer Research

IF:10 CiteScore:20.1 Articles:1207
Clinical Cancer Research is a journal focusing on groundbreaking research in cancer, specifically in the areas where the laboratory and the clinic intersect. Our primary interest lies in clinical trials that investigate novel treatments, accompanied by research on pharmacology, molecular alterations, and biomarkers that can predict response or resistance to these treatments. Furthermore, we prioritize laboratory and animal studies that explore new drugs and targeted agents with the potential to advance to clinical trials. We also encourage research on targetable mechanisms of cancer development, progression, and metastasis.

The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models

Published: 25 October 2016 DOI: 10.1158/1078-0432.CCR-16-0569
Sen Zhang,?R. Anjum,?R. Squillace,?S. Nadworny,?T. Zhou,?J. Keats,?Y. Ning,?Scott D. Wardwell,?David Miller,?Youngchul Song,?Lindsey W. Eichinger,?Lauren Moran,?Wei-sheng Huang,?Shuangying Liu,?D. Zou,?Yihan Wang,?Qurish K. Mohemmad,?H. G. Jang,?E. Ye,?N. Narasimhan,?Frank Y. Wang,?J. Miret,?Xiaotian Zhu,?T. Clackson,?D. Dalgarno,?W. Shakespeare,?V. Rivera