天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook >> journal list >> Sensors and Actuators B: Chemical >>article
Sensors and Actuators B: Chemical

Sensors and Actuators B: Chemical

IF: 8
Download PDF

Portable, Facile Microfluidic Platform Using a Low-Cost Vacuum Pump for Multiplex Biomarker Detection in Human Samples

Published:22 November 2024 DOI: 10.1016/j.snb.2024.136994
Bo Liu, Jing Jin, Yonggang Zhu

Abstract

Portable multiplex microfluidic platforms are critically needed for point-of-care testing (POCT) of health-related biomarkers. The complex preparation processes and the use of expensive and bulky devices lead to increased detection costs, hindering the application of emerging POCT technologies. Here, we introduce a portable and versatile microfluidic platform for low-cost multiplex biomarker detection, integrated with a facile and easy-to-operated vacuum pump and mass-produced screen-printed carbon electrodes (SPCEs). The innovative pump, comprising only a syringe, a valve, and a spring, costs approximately $0.50. It operates by using the compressed spring to self-sufficiently drive reagents, which are actuated via a valve switch. The pump's performance was assessed under various conditions, demonstrating consistent operation and a broad pressure range. Additionally, electrocatalytic nanocomposites (Ti3C2Tx/Pt-Pd) were adopted to modify the SPCEs, resulting in high-efficiency performance (<15?min), cost-effectiveness (<$4 per test) and excellent reliability across a broad detection scope. Finally, the platform successfully achieved multiplex detection of biomarkers (glucose, uric acid and lactic acid) in serum, sweat and saliva. This simple and adaptable platform promises to facilitate cost-effective, multiplex biomarker detection, paving the way for large-scale POCT applications, particularly in resource-limited settings.

Substances (2)

Materials
Procduct Name CAS Molecular Formula Supplier Price
Ascorbic Acid 50-81-7 C6H8O6 1627 suppliers $6.00-$2170.00
Glucose oxidase 9001-37-0 NULL 357 suppliers $66.10-$3200.00