天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook >> journal list >> Current topics in medicinal chemistry >>article
Current topics in medicinal chemistry

Current topics in medicinal chemistry

IF: 2.89
Download PDF

Synthesis of Isatin-derived Heterocycles with Promising Anticancer Activities.

Published:8 August 2024 DOI: 10.2174/0115680266311332240722065652 PMID: 39129163
Bubun Banerjee,?Aditi Sharma,?Arvind Singh,?Manmeet Kaur,?Anu Priya

Abstract

Isatin or 1H-indole-2,3-dione skeleton has been playing a significant role in drug de-sign and development. Isatin itself and many of its derivatives are widely distributed in naturally occurring bioactive compounds. Various synthetic isatin derivatives were found to possess a broad range of significant pharmacological efficacies especially anti-cancer activity against a wide variety of cancer cell lines. Interestingly, on a few occasions, some isatin-derived scaffolds were reported as more potent than the tested reputed drug molecules. As a result, isatin-derived compounds have been gaining significant attention in cancer-based drug developments. In this re-view, we have summarized literature reported during the last two decades related to the synthesis of structurally diverse isatin-derived scaffolds with promising anti-cancer activities.

Substances (6)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Isatin 91-56-5 C8H5NO2 540 suppliers $5.00-$5425.00
5-(TRIFLUOROMETHYL)ISATIN 345-32-4 C9H4F3NO2 151 suppliers $57.00-$879.93
ANKAFLAVIN 50980-32-0 C23H30O5 62 suppliers Inquiry
Bioactive Compound Library 6 suppliers Inquiry
V1A CA CELL LINES 4 suppliers Inquiry
Perfecta3D hanging drop plate 2 suppliers $38.30-$234.00

Similar articles

IF:4.2

Tetrabutylammonium Bromide (TBAB) Catalyzed Synthesis of Bioactive Heterocycles.

Molecules Bimal Krishna Banik,?Bubun Banerjee,etc Published: 14 December 2020
IF:1.8

Synthesis of 2-Aminobenzophenone Derivatives and Their Anticancer Activity

Synthetic Communications Sandra Cortez-Maya,?E. Cortés,etc Published: 1 January 2012
IF:3.2

Emodin - A natural anthraquinone derivative with diverse pharmacological activities

Phytochemistry Ruchi Badoni Semwal , Deepak Kumar Semwal ,etc Published: 1 October 2021