How much L-Norvaline should an adult take per day?
Dec 12,2024
L-Norvaline is a natural amino acid active ingredient with blood flow-improving properties, particularly for athletic people. L-Norvaline promotes the production of arginine, which is required for the production of nitrate, which is essential for efficient blood flow and helping arteries relax. To meet physiological needs, the adult body should take in about 25 mg/kg of valine per day, which is equivalent to about 2 g of valine per day for an adult. In addition, the concentration of L-valine in the cerebrospinal fluid (CSF) of healthy people is about 20 μM, which is far lower than the cytotoxic concentration of L-norvaline (>125 μM). Athletes use L-norvaline at doses between 200 and 300 mg/day, which is about 10 times lower than the usual intake of L-valine.
References:
[1] BARUH POLIS Abraham O S Michael A Gilinsky. Reports of L-Norvaline Toxicity in Humans May Be Greatly Overstated.[J]. ACS Applied Bio Materials, 2019. DOI:10.3390/brainsci9120382.
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