Zinc pyrithione (or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (that is, it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.

If you’re dealing with pesky fungal acne, here’s how using a product with zinc pyrithione may help.

Fight fungus. Zinc pyrithione is known for its antifungal properties, which could make it especially useful for treating fungal acne.

Reduce inflammation and fight bacteria. Its antimicrobial properties might help fight off bacteria, an OG cause of acne, and any inflammation that make pimples more irritated.

May decrease oil production. Research from 2013 suggests that topical forms of zinc may help decrease oil production, which may help reduce the risk of clogged pores and pimples.

Treats eczema and psoriasis. If you’re also dealing with dry, inflamed skin probs from eczema or psoriasis, zinc pyrithione has proven benefits. According to a 2014 study, using 2.5 percent zinc pyrithione twice a day is useful in treating plaque psoriasis. Some 2021 research also shows it can be an effective eczema treatment.

Mechanism of action

Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.

Health effects

Use of zinc pyrithione is prohibited in European Union since Dec.01.2021 (ANNEX II , Lastupdate:01/12/2021 List of substances prohibited in cosmetic products).

Zinc pyrithione is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several anti-dandruff shampoos and body wash gels. In its industrial forms and strengths, it may be harmful by contact or ingestion. Zinc pyrithione can trigger a variety of responses, such as DNA damage in skin cells.