N3-PEG-COOH
1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid
中文名稱:疊氮-八聚乙二醇-丙酸
CAS No 1214319-92-2
MDL number:MFCD21363300
分子式:C19H37N3O10
分子量:467.5
純 度:95%+
結(jié)構(gòu)式:
產(chǎn)品簡(jiǎn)介:
Azido-PEG8-acid,1214319-92-2是一種點(diǎn)擊化學(xué)試劑。分子一端的疊氮化物部分可用于銅(I)催化的點(diǎn)擊化學(xué)或無(wú)銅點(diǎn)擊化學(xué)。在分子另一端的疊氮化物部分和丙酸部分之間是單分子量的離散聚乙二醇(dPEG?)間隔基。丙酸部分可通過(guò)?;磻?yīng)與伯胺或仲胺偶聯(lián)。
N3-PEG8-COOH,CAS:1214319-92-2,Azido-PEG8-acid contains an azide function on one end of a single molecular weight dPEG? spacer (32.2?) and a reactive group on the other end of the spacer. The dPEG? spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
性狀:固體或粘性液體
用 途:僅供科研實(shí)驗(yàn)使用,不用于診治
注意事項(xiàng):取用一定要干燥,避免頻繁的溶解和凍干
溶解性:溶于大部分有機(jī)溶劑,如:DCM、DMF、DMSO、THF等等。在水中有很好的溶解性。
其它類(lèi)似化合物:
Azido-PEG1-acid 1393330-34-1
Azido-PEG2-acid 1312309-63-9
Azido-PEG3-acid 1056024-94-2
Azido-PEG4-acid 1257063-35-6
Azido-PEG5-acid 1425973-16-5
Azido-PEG6-acid 361189-66-4
Azido-PEG8-acid 1214319-92-2
Azido-PEG9-acid 1670249-37-2
Azido-PEG10-acid 1644163-57-4
Azido-PEG12-acid 1167575-20-3
Azido-PEG24-acid 1167575-20-3
Azido-PEG36-acid 1167575-20-3