Product Name: (-)-Corey lactone diol
Synonym: (-) COREY LACTONE DIOL;(-)-COREY LACTONE DIOL,98%;(3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,;(1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone;(1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one;(3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one;(-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one,98%;(+)-6β-Hydroxymethyl-7α-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
MF: C8H12O4
MW: 172.18
Product Category: Latanoprost;Prostaglandins;API
Melting Point: 117-119 °C(lit.)
Boiling Point: 262.49°C (rough estimate)
Density: 1.2104 (rough estimate)
Refractive Index: 1.4455 (estimate)
Storage Temp.: -20°C
Form: Crystalline Powder or Crystals
pKa: 14.36±0.40(Predicted)
Color: White to beige-brown
Optical Activity: [α]20/D 44°, c = 1.4 in methanol
InChlKey: VYTZWRCSPHQSFX-GBNDHIKLSA-N
Safety Statements: 24/25
WGK Germany: 3
Chemical Property: white to beige-brown cryst. powder or crystals
Uses: (-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmo nary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
關(guān)鍵字： 中間體;
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