Alanine Racemase (Crude Enzyme)
Alanine Racemase，中文名為丙氨酸消旋酶，催化L-丙氨酸與D-丙氨酸之間相互轉(zhuǎn)化。本產(chǎn)品為大腸桿菌表達(dá)的丙氨酸消旋酶，并經(jīng)簡(jiǎn)單純化獲得的可以確保達(dá)到一定酶活力的粗酶液。
由于本產(chǎn)品需新鮮制備，確認(rèn)訂購(gòu)后約6個(gè)工作日才可以發(fā)貨。個(gè)別情況首次制備出現(xiàn)問題，發(fā)貨時(shí)間會(huì)順延。
本產(chǎn)品可以提供十公斤、百公斤乃至噸級(jí)的粗酶液，如有需求請(qǐng)聯(lián)系康朗。
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. This enzyme participates in alanine and aspartatemetabolism and D-alanine metabolism. It employs one cofactor, pyridoxal phosphate. At least two compounds, 3-Fluoro-D-alanine and D-Cycloserine are known to inhibit this enzyme.The D-alanine produced by alanine racemase is used for peptidoglycan biosynthesis. Peptidoglycan is found in the cell walls of all bacteria, including many which are harmful to humans. The enzyme is absent in higher eukaryotes but found everywhere in prokaryotes, making alanine racemase a great target for antimicrobial drug development.Alanine racemase can be found in some invertebrates.Bacteria can have one (alr gene) or two alanine racemase genes. Bacterial species with two genes for alanine racemase have one that is continually expressed and one that is inducible, which makes it difficult to target both genes for drug studies. However, knockout studies have shown that without the alr gene being expressed, the bacteria would need an external source of D-alanine in order to survive. Therefore, the alr gene is a feasible target for antimicrobial drugs. This product with the indicated enzyme activity was briefly purified from engineered E.coli.
產(chǎn)品詳細(xì)信息見下表:
Name
Alanine Racemase (Crude Enzyme)；丙氨酸消旋酶(粗酶液)
Application
催化L-丙氨酸與D-丙氨酸之間相互轉(zhuǎn)化
Appearance
Clear to translucent yellow solution
Enzyme activity
Undetermined
Name
Alanine Racemase；丙氨酸消旋酶
Enzymatic Reaction
L-alanine = D-alanine
Synonyms
L-alanine racemase
Systematic name
alanine racemase
Cofactor(s)
pyridoxal 5'-phosphate
Application
drug development; pharmacology; medicine; pharmacology
包裝清單：
產(chǎn)品編號(hào)
產(chǎn)品名稱
包裝
KL3807-100ml
Alanine Racemase (Crude Enzyme)
100ml
KL3807-1L
Alanine Racemase (Crude Enzyme)
1L
保存條件：
-20℃或更低溫度保存，至少1個(gè)月有效。
注意事項(xiàng)：
由于本產(chǎn)品需新鮮制備，在您確認(rèn)訂購(gòu)后約6個(gè)工作日才能發(fā)貨。個(gè)別情況首次制備出現(xiàn)問題，發(fā)貨時(shí)間會(huì)順延。
粗酶液的每次凍融均可能會(huì)引起部分失活，所以收到酶液后請(qǐng)根據(jù)需要進(jìn)行分裝，并置于-20℃或更低溫度保存。
隨著保存時(shí)間的延長(zhǎng)，酶活力會(huì)有一定程度的下降，收到產(chǎn)品后應(yīng)盡快使用。
本產(chǎn)品在生產(chǎn)和保存的過程中可能會(huì)有混濁或沉淀產(chǎn)生，融化后混勻即可，不影響正常使用。
本產(chǎn)品僅限于專業(yè)人員的科學(xué)研究用，不得用于臨床診斷或治療，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
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關(guān)鍵字： Alanine Racemase (Crude Enzyme)說明書；Alanine Racemase (Crude Enzyme)廠家
上?？道噬锟萍加邢薰臼且患壹邪l(fā)、生產(chǎn)、銷售、服務(wù)于一體的一家生物科技企業(yè)，專營(yíng)生化試劑、標(biāo)準(zhǔn)品、基因、蛋白、抗體、Elisa試劑盒、細(xì)胞生物學(xué)，分子生物學(xué)等高生物產(chǎn)品?？偛课挥谏虾?，并在北京、廣東，江西，吉林等全國(guó)30多個(gè)省市設(shè)有分公司和代理機(jī)構(gòu)。涉及的產(chǎn)品被中國(guó)科學(xué)院、清華、北大、復(fù)旦，上海交大，復(fù)旦醫(yī)學(xué)院，上海中醫(yī)藥大學(xué)，華東師范大學(xué)，第二軍醫(yī)大學(xué)，曙光醫(yī)院，浦東新區(qū)人民醫(yī)院等知名科研院所廣泛使用，可靠而穩(wěn)定的質(zhì)量和完善的售后服務(wù)確。