產(chǎn)品英文名稱：
Recombinant Human Centromere Protein-B

英文簡稱:
CENPB

中文名稱:
重組人著絲粒蛋白-B

背景資料:
Centromere proteins are a group of proteins which form and/or mediate the function of centromeres， the central structures of chromosomes to which spindle fibers/microtubuli attach and pull the chromosomes apart in cell division. Currently， 9 centromere proteins are known and designated CENPA to CENP-I. Most of the centromere proteins are targets of autoantibodies， the anti-centromere antibodies.CENPB is the most important of the centromeric autoantigens: it has a molecular weight of approx. 66 kDa and plays an important role in the formation of the centromeric chromatin. CENPB antibodies are present in the sera of up to 80% of patients with CREST syndrome.

產(chǎn)品描述:
CENPB Human Recombinant produced in SF9 is a glycosylated， polypeptide chain having a molecular mass of 65，940 Dalton.CENPB is expressed with a -6x His tag and purified by proprietary chromatographic techniques.
來源宿主:
昆蟲Sf9細(xì)胞中重組表達(dá)

序列:


溶解建議:
Sterile Filtered liquid formulation. CENPB is supplied in 20mM HEPES buffer pH-7.6， 250mM sodium chloride， and 20% glycerol.

保存建議：
Store at 4℃ if entire vial will be used within 2-4 weeks.Store， frozen at -20℃ for longer periods of time.Avoid multiple freeze-thaw cycles.
其他簡介：

? ProSpec是一家全球著名細(xì)胞因子蛋白及相關(guān)抗體生產(chǎn)和研發(fā)品牌。ProSpec的生產(chǎn)和研發(fā)工廠位于以色列，專注于蛋白（重組及合成）生產(chǎn)研發(fā)，其獨(dú)有的細(xì)菌和哺乳動物表達(dá)和蛋白折疊技術(shù)使其能在17年內(nèi)成長為國際一流的科研級蛋白供應(yīng)商。目前ProSpec可以提供細(xì)胞因子，生長因子，激素，信號蛋白，病毒抗原等近800種重組蛋白和100多種抗體，是世界上提供蛋白品種最多的公司之一，領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級蛋白，價(jià)格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護(hù)劑或鹽，這就對工藝提出了更高的要求。同時(shí)，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。