美國(guó) Cell Signaling Technology（CST）?

美國(guó) Cell Signaling Technology（CST）是最知名的和老牌的信號(hào)轉(zhuǎn)導(dǎo)公司之一，專注于信號(hào)轉(zhuǎn)導(dǎo)產(chǎn)品的提供和研究。產(chǎn)品具有種類多、質(zhì)量好、價(jià)格低、引用文獻(xiàn)多等優(yōu)點(diǎn)，是您進(jìn)行信號(hào)轉(zhuǎn)導(dǎo)研究不可多得的幫手！
提供特色的信號(hào)傳導(dǎo)用磷酸化檢測(cè)抗體、ELISA檢測(cè)試劑盒、活性的重組激酶等藥篩產(chǎn)品。涉及的細(xì)胞信號(hào)通路有： 1 染色質(zhì)調(diào)控與乙酰化信號(hào)通路 2 MAP激酶信號(hào)網(wǎng)絡(luò) 3 SAPK/JNK信號(hào)通路 4 細(xì)胞凋亡與Caspase信號(hào)網(wǎng)絡(luò) 5 AKT信號(hào)網(wǎng)絡(luò) 6 轉(zhuǎn)錄與翻譯調(diào)控 7 蛋白激酶C PKC 信號(hào)網(wǎng)絡(luò) 8 周期調(diào)控與DNA損傷信號(hào)通路 9 細(xì)胞骨架調(diào)控 10 白細(xì)胞信號(hào)傳導(dǎo)，等等。
主要產(chǎn)品：
抗體類：提供超過(guò)1300種磷酸化和非磷酸化抗體，具有最多的磷酸化抗體，同時(shí)提供sample kit和phosphoPlus Ab kit
ELISA試劑盒：PathScan Sandwich ELISA Kit系列產(chǎn)品是檢測(cè)蛋白磷酸化水平的ELISA試劑盒，靈敏度高，操作簡(jiǎn)單
WB用蛋白Marker：CST的Biotinylated Protein Ladder Detection Pack產(chǎn)品包括有10個(gè)條帶、大小在10-200Kda之間的生物素標(biāo)記蛋白標(biāo)準(zhǔn)和HRP藕聯(lián)的抗生物素二抗（anti-biotin antibody, HRP-linked），有大小兩種包裝可選
kinase assay kit：試劑盒組成合理全面，非同位素操作，應(yīng)用起來(lái)簡(jiǎn)單方便。
buffer類：共有6個(gè)buffer類，是進(jìn)行普通WB或磷酸化WB檢測(cè)的必須輔助試劑，用于標(biāo)本蛋白的制備。
激酶類：多種形式的蛋白激酶，可以用于藥物篩選
藥物篩選試劑盒：高通量、針對(duì)激酶的藥物篩選
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The genomic era has yielded a wealth of new genes for which function and inter-relationships remain unknown. At the same time there is an increasing appreciation of the limits of what can be learned from gene expression profiling, and of the need to examine protein expression and activity. Activation-state-specific antibodies have proven to be a convenient and reliable set of tools in the new post-genomic "research toolbox". Cell Signaling Technology, Inc. （CST） is committed to developing innovative new research tools such as these to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine.

CST strives to make novel antibodies of the highest possible quality by producing them in-house and rigorously characterizing them with respect to specificity and sensitivity. Production begins with extensive purification （typically by both protein A and peptide affinity chromatography） followed by testing by our staff scientists on a wide range of applications, including ELISA, western blotting, immunoprecipitation, immunocytochemistry, immunohistochemistry and flow cytometry. Technical support is provided by the very scientists who make a given antibody and know it best. CST scientists are also responsible for creating most of the cell signaling reference material, including pathways, kinase trees and kinase disease associations that we offer our customers in the last chapter of this catalog and on our website.