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Anti-B4GALT1 Polyclonal Antibody,Anti-B4GALT1 Polyclonal Antibody
  • Anti-B4GALT1 Polyclonal Antibody,Anti-B4GALT1 Polyclonal Antibody

Anti-B4GALT1 Polyclonal Antibody

價(jià)格 960.00 1600.00
包裝 50ul 100ul
最小起訂量 50ul
發(fā)貨地 北京
更新日期 2024-12-27
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產(chǎn)品詳情

中文名稱:Anti-B4GALT1 Polyclonal Antibody英文名稱:Anti-B4GALT1 Polyclonal Antibody
Gene ID: 2683Public Immunogen Range: Recombinant protein of human B4GALT1
Swiss Prot: P15291保存: Store at -20°C. Avoid freeze / thaw cycles.
別名: B4GAL-T1;CDG2D;GGTB2;GT1;GTB;beta4Gal-T1產(chǎn)品編號(hào): K005906P
儲(chǔ)存液: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.純化方法: Affinity purification
蛋白分子量: 44kDa交叉反應(yīng): Human
克隆類型: Polyclonal Antibody免疫原: Recombinant protein of human B4GALT1
品牌: solarbio宿主: Rabbit
稀釋比例: WB 1:500-2000.性狀: 液體
亞型: IgG應(yīng)用: WB
英文名稱: Anti-B4GALT1 Polyclonal Antibody
2024-12-27 Anti-B4GALT1 Polyclonal Antibody Anti-B4GALT1 Polyclonal Antibody 50ul/960.00RMB;100ul/1600.00RMB 960.00

Subcellular Locations

Cell membrane Cell projection Cell surface Golgi apparatus Golgi stack membrane Secreted Single-pass type II membrane protein filopodium

背景資料

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose < > UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.
關(guān)鍵字: Anti-B4GALT1 Polyclonal Antibody;抗體

公司簡(jiǎn)介

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成立日期 2004-09-22 (21年) 注冊(cè)資本 1000萬元
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