Anti-TSG101 antibodyCat. No. ?? JC121387 ? ? ? ?
Package?? ?25 μl/100 μl/200 μl
Storage?? ?-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description ? ? ? ? ? ? ? ?? ?Anti-TSG101 rabbit polyclonal antibody
Applications ? ??? ?ELISA, IHC?
Immunogen ? ? ? ? ? ?? ?Fusion protein of human TSG101
Reactivity ? ? ? ? ? ? ?? ?Human, Mouse, Rat
Content ? ? ? ? ? ? ? ? ?? ?0.2 mg/ml
Host species ? ? ? ? ? ?? ?Rabbit
Ig class ? ? ? ? ? ? ??? ?Immunogen-specific rabbit IgG
Purification ? ? ? ? ? ? ?? ?Antigen affinity purification
Anti-TSG101 antibodyTarget information
Symbol ? ? ? ? ? ? ?? ?TSG101
Full name ? ? ? ? ? ? ?? ?tumor susceptibility 101
Synonyms?? ?TSG10; VPS23
Swissprot?? ?Q99816
Target Background
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Anti-TSG101 antibodyApplications
Immunohistochemistry
Predicted cell location: Cytoplasm or Nucleus
Positive control: Human brain
Recommended dilution: 25-100?? ?Predicted cell location: Cytoplasm or Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 25-100
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