B-1080 Bafilomycin A1, >98%
M.W. 622.83
C35H58O9
[88899-55-2]
Storage:? Store at or below -20 oC.? Solubility:? Soluble in DMSO at 200 mg/mL; may react with methanol or ethanol, so these solvents are not recommended for stock solutions; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10 μM; buffers, serum, or other additives may increase or decrease the aqueous solubility.? Appearance:? Clear film.? Disposal:? A
Specific, potent inhibitor of vacuolar ATPases.? Bowman, E.J., et al.? "Bafilomycins: A class of inhibitors of membrane ATPase from microorganisms, animal cells, and plant cells."? Proc. Natl. Acad. Sci. USA 85:? 7972-7976 (1988).
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