Species

Gene ID

Accession

Source

Length

MW

Tag

Rat

117518

Q9ERE0

E. coli

70aa

8.1kDa

－

About this Antibody

Name

Recombinant Rat TARC/CCL17 (Recombinant Rat Thymus and Activation Regulated Chemokine/CCL17; rRtTARC/CCL17)；重組大鼠胸腺活化調節(jié)趨化因子/CCL17

Synonyms

TARC; ABCD-2; CC chemokine TARC; C-C motif chemokine 17; chemokine (C-C motif) ligand 17; MGC138273; SCYA17MGC138271; small inducible cytokine subfamily A (Cys-Cys), member 17; Small-inducible cytokine A17; T cell-directed CC chemokine; TARCA-152E5.3; Thymus and activation-regulated chemokine

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 0.1EU/μg of r rRtTARC/CCL17 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CCL17 also known as thymus and activation-related chemokine (TARC) is encoded by the CCL17 gene located on the chromosome 16. It is expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently. CCL17 signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes. It plays an important role in skin diseases such as atopic dermatitis, bullous pemphigoid and mycosis fungoides. CCL17 has approximately 24-29% amino acid sequence identity with RANTES, MIP-1α, MIP-1β, MCP-1, MCP-2, MCP-3 and I-309.

Amino Acid Sequence

ARATNVGREC CLDYFKGAIP IRKLVTWFRT SVECPKDAIV FETVQGRLIC TDPKDKHVKK AIRHLKNQRL

產品編號

產品名稱

包裝

P6929-5μg

Recombinant Rat TARC/CCL17

5μg

P6929-20μg

Recombinant Rat TARC/CCL17

20μg

P6929-100μg

Recombinant Rat TARC/CCL17

100μg

P6929-1mg

Recombinant Rat TARC/CCL17

1mg

-

說明書

1份