背景資料

HDAC family are divided into two classes， I and II. Class I of the HDAC family comprises four members， HDAC-1， 2， 3， and 8. Class II of the HDAC family comprises HDAC-4， 5， 6， and 7， the molecular weights of which are all about two-fold larger than those of the class I members. Human HDAC-1， 2 and 3 were expressed in various tissues， but the others （HDAC-4， 5， 6， and 7） showed tissue-specific expression patterns. These results suggest that each member of the HDAC family exhibits a different， individual substrate specificity and function in vivo.

應(yīng)用類型

Western blotting （0.5-4 ug/ml）， However， the optimal concentrations should be determined individually. The antibody recognizes 74 kDa HDAC-10 of human， mouse， and rat origins. A 55 kDa cleavage fragment can also be detected in mouse and rat tissue lysates.

免疫原

Synthetic peptide near the N-terminus of human HDAC-10

來源宿主

兔

反應(yīng)性

經(jīng)檢測驗證，可與人、小鼠、大鼠種屬來源的HDAC10蛋白發(fā)生免疫反應(yīng).

保存建議

提供的HDAC10抗體產(chǎn)品為100 ug 無色溶液，其濃度為0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS緩沖液中.請將該HDAC10抗體產(chǎn)品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融.