Bemotrizinol Tinosorb S CAS NO. 187393-00-6 / CELL/WHATSAPP: 0086-13968006641 GRACE@KNIKTECH.COM
Bemotrizinol
Names |
IUPAC name
2,2′-[6-(4-methoxyphenyl)- 1,3,5-triazine-2,4-diyl] bis{5-[(2-ethylhexyl)oxy]phenol}
Other names
Tinosorb S
Bis-ethylhexyloxyphenol methoxyphenyl triazine
Anisotriazine
Identifiers |
- 187393-00-6
ChEBI
- CHEBI:135857
ChEMBL
- ChEMBL2104956
ChemSpider
- 10645286
ECHA InfoCard
100.109.468
- 11954320 also 73951545, 21896073
UNII
- PWZ1720CBH
Properties |
Hazards |
GHS precautionary statements
P273, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Bemotrizinol (INN[1][2]/USAN,[3] INCI bis-ethylhexyloxyphenol methoxyphenyl triazine) is an oil-soluble organic compound that is added to sunscreens to absorb UV rays. It is marketed as Tinosorb S by BASF and as Escalol S by Ashland Inc. A recent development is Tinosorb S Aqua, which is bemotrizinol in a PMMA matrix dispersed in water. This makes it possible to add bemotrizinol to the water phase.[4]
Bemotrizinol is a broad-spectrum UV absorber, absorbing UVB as well as UVA rays. It has two absorption peaks, 310 and 340 nm.[5] It is highly photostable. Even after 50 MEDs (minimal erythemal doses), 98.4% remains intact. It helps prevent thephotodegradation of other sunscreen actives like avobenzone.[6]
Bemotrizinol has strong synergistic effects on the SPF when formulated with bisoctrizole, ethylhexyl triazone oriscotrizinol.[7] It is the most effective UV absorber available measured by SPF, based on the maximum concentration permitted by European legislation.[8]
Bemotrizinol is not approved by the United States Food and Drug Administration, but is approved in the European Union since the year 2000[9] and other parts of the world, including Australia.[10][11]
Unlike some other organic sunscreen actives, it shows no estrogenic effects in vitro.[12]